Pilot Study of Taste Sensations in Patients With End-stage Renal Disease on Hemodialysis
Launched by PURDUE UNIVERSITY · Apr 4, 2018
Trial Information
Current as of May 15, 2025
Completed
Keywords
ClinConnect Summary
A. Background:
Individuals on dialysis due to kidney failure have very prescriptive diets. These diets help increase dialysis effectiveness and help patients control blood levels of electrolytes including potassium and phosphate, acid-base balance, blood pressure, and fluid between dialysis treatments. However, patient compliance with these diets is often very low, and one reason for this low compliance is disguesia (abnormal taste sensations) which can make the diets unpalatable. The investigators hypothesize this disguesia, and subsequent lack of adherence to a dialysis friendly diet, is...
Gender
ALL
Eligibility criteria
- HD subjects:
- • Inclusion
- • Men and women
- • Any race
- • Age 18 years or older
- • Maintenance hemodialysis patients
- • Exclusion
- • • Patients with dysphagia who are not able consume the test solutions (clear, thin liquids).
- Control subjects:
- • Inclusion
- • No tongue, lip, or cheek piercings
- • Over 18 years of age
- • Normal taste and smell function
- • No known issues with salivation or dry mouth
- • Willing to comply with study protocol (taste samples and provide saliva)
About Purdue University
Purdue University is a renowned research institution dedicated to advancing knowledge and innovation across various fields, including health and medicine. As a clinical trial sponsor, Purdue leverages its extensive academic resources and multidisciplinary expertise to conduct rigorous research aimed at improving patient outcomes and contributing to the scientific community. With a commitment to ethical standards and regulatory compliance, Purdue University collaborates with healthcare professionals and industry partners to translate research findings into practical applications, ultimately enhancing the quality of care and addressing critical health challenges.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
West Lafayette, Indiana, United States
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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