EMR-C VS EMR-S in Colonic Lateral Spreading Tumors Treatment (LST)

Launched by AZIENDA OSPEDALIERA UNIVERSITARIA SENESE · Apr 7, 2018

Keywords

ClinConnect Summary

Colorectal carcinoma (CRC) is the second cause of death for cancer in industrialized countries, with annual incidence and mortality of about one million and 500.000 case respectively.

It's well known that most of CRC follow the path adenoma-carcinoma: early diagnosis and endoscopic removal of colonic polyps has been proved to be useful in preventing cancer.

Most of colorectal polyps are smaller than 1 cm and can be successfully resected with a standard polypectomy. However, between 0.8% and 5% of patients develop sessile polyps or lesions larger than 20 mm, of which removal can be difficu...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients ≥18 years Colonic LST-G/NG () ≥ 30 mm in size. Patients able to undergo all follow up procedures as indicated in the protocol and to provide written informed consent, at least 48 hours before the intervention (reasoned consent).
• Exclusion Criteria:
• • Presence of sessile polyps Non polypoid lesions 0-III according to Paris Classification Lesions with suspicion of malignancy (rigidity, non-lifting lesions, mucosal fragility, ulceration) Patients unable to provide informed consent Patients with coagulopathy and INR \>1.5 (not corrected with replacement therapy, such as enoxaparin).
• • Patients who have undergone previous attempt of lesion resection (residual disease, local recurrence).
• • Patients with histological diagnosis of submucosal invading neoplasia who will be sent to surgery and excluded from follow-up.