Effects of a Multi-ingredient Supplement Study: a Randomized Controlled Trial in Men and Women

Launched by MCMASTER UNIVERSITY · May 3, 2018

Keywords

ClinConnect Summary

Supplementation in the form of whey protein, creatine and amino acids have all been shown to be a potent stimulus for muscle hypertrophy, when combined with resistance exercise. Burke et al. (2001) reported that males who supplemented with a combination of whey protein and creatine had greater increases in lean tissue mass and strength than those who supplemented with only whey protein or placebo. Hulmi at al. (2010) identified the most important component of whey to be its high concentration of the branched chain amino acid leucine, a critical amino acid for increasing muscle protein synth...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Aged 18-30 years old
• • Healthy based on questionnaire responses (see exclusion criteria)
• • Recreationally active (exercising \~2x/week) with some resistance training experience (no more than 2 times weekly) allowed
• Exclusion Criteria:
• • Any acute or chronic illness, cardiac, pulmonary, liver, or kidney abnormalities, uncontrolled hypertension, insulin- or non-insulin dependent diabetes or other metabolic disorders-all ascertained through medical history screening questionnaires
• • Arthritic conditions
• • Individuals who consume any analgesic or anti-inflammatory drug(s), prescription or non-prescription, chronically will be excluded
• • A history of neuromuscular complications
• • Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications).
• • Extensive history of resistance training in the year prior to study entry.
• • Answers 'yes' to any question on the screening questionnaire