Refractive Corneal Cross-linking for Progressive Keratoconus
Launched by MOORFIELDS EYE HOSPITAL NHS FOUNDATION TRUST · May 8, 2018
Trial Information
Current as of May 15, 2025
Completed
Keywords
ClinConnect Summary
Irregular astigmatism (irregular corneal shape leading to irregular focus) is a common cause of failure to achieve an adequate spectacle correction for many patients with corneal disease. For patients affected, rigid gas permeable contact lenses are the only means of visual rehabilitation. Not all patients tolerate rigid contact lens wear, and those that do are often uncomfortable and have a restricted wearing time.
Keratoconus, in which the corneal shape becomes progressively steeper and more irregular in the 2nd to 4th decades of life, is a common cause of irregular astigmatism. Disease ...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients with progressive stage I - III keratoconus
- • Corrected distance visual acuity (CDVA) \< 0.00 logMAR
- Exclusion Criteria:
- • Patients under the age of 18 years
- • Active ocular surface disease
- • Minimum corneal thickness \< 375 µm
- • Vulnerable groups
- • Pregnancy
About Moorfields Eye Hospital Nhs Foundation Trust
Moorfields Eye Hospital NHS Foundation Trust is a leading specialist eye hospital located in London, renowned for its commitment to advancing ophthalmic research and clinical care. As a prominent clinical trial sponsor, Moorfields is dedicated to improving patient outcomes through innovative research, employing cutting-edge technology and methodologies in the field of ophthalmology. The institution collaborates with a diverse range of partners, including academic institutions and industry stakeholders, to facilitate groundbreaking studies aimed at developing new treatments and therapies for various eye conditions. With a strong focus on patient safety and ethical standards, Moorfields Eye Hospital remains at the forefront of eye care, driving progress in the understanding and management of visual impairments.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
London, , United Kingdom
Patients applied
Trial Officials
Daniel M Gore
Principal Investigator
Moorfields Eye Hospital NHS Foundation Trust
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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