Detection of Chlamydia Trachomatis, Neisseria Gonorrhoeae and Mycoplasma Genitalium by Real-time Multiplex Polymerase Chain Reaction (PCR) After Pooling Pharyngeal, Anorectal and Urinary Samples

Launched by CENTRE HOSPITALIER RÉGIONAL D'ORLÉANS · Jun 14, 2018

Keywords

ClinConnect Summary

Patients detected positive for one of the three (Sexually Transmitted Infection)STIs (Chlamydia trachomatis, Neisseria gonorrhoeae or Mycoplasma genitalium) on one site will be re-sampled twice at each of the three sites (pharynx, rectum, urine) before receiving antibiotics. Then, a real-time multiplex PCR will be performed on the pooled sample (merging pharyngeal, anorectal and urinary samples) versus on each of the three samples separately (i.e. standard of care) to compare both sensitivities.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Patient having provided a written consent;
• • Patient age \> 18 years;
• • Man who have sex with men tested positive for one the three STIs : Chlamydia trachomatis, Neisseria gonorrhoeae or Mycoplasma genitalium
• • Covered by health insurance
• Exclusion Criteria:
• • Being under tutorship
• • Being deprived of liberty
• • Patient who received antibiotic treatment prior to study inclusion and re-sampling