Autocorrelated Rhythmic Auditory Stimulations for Parkinson's Disease Patients

Launched by CLINIQUES UNIVERSITAIRES SAINT-LUC- UNIVERSITÉ CATHOLIQUE DE LOUVAIN · Oct 22, 2018

Keywords

ClinConnect Summary

BACKGROUND

Basal Ganglia dysfunction in Parkinson's Disease (PD) induces gait impairment such as shorter stride length, reduced gait speed, reduced arm swing and an increased randomness in stride duration variability of gait cycles. This increased randomness in gait variability is a typical symptom which can lead to falls, autonomy loss and reduced quality of life. Recently, the Long-Range Autocorrelations (LRA) assessment allowed to emphasize the deterioration of the temporal organization of PD patients' gait variability and demonstrated correlations with disease severity and balance stat...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Idiopathic Parkinson's Disease according to UK Brain Bank criteria
• • A modified Hoehn \& Yahr scale between 1 and 3
• • Able to walk for at least 10 minutes in a row
• • Dopaminergic was stable for a minimum of 4 weeks before the study starts
• • A Mini-Mental State Examination (MMSE) \>24
• Exclusion Criteria:
• • Severe co-morbidity, other neurological problems, acute medical problems (e.g. MI, diabetes) and joint problems affecting mobility
• • Unpredictable "Off"-periods (score \>2, MDS-UPDRS item 4.5)