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Search / Trial NCT03733262

Targeted Deprescribing in Patients on Hemodialysis

Launched by UNIVERSITY HEALTH NETWORK, TORONTO · Nov 5, 2018

Trial Information

Current as of May 03, 2025

Recruiting

Keywords

Deprescribing Hemodialysis Medication Optimization Medication Prescribing Patterns Patient Safety Polypharmacy Pill Burden Quality Improvement Activity Chronic Kidney Disease End Stage Renal Disease

ClinConnect Summary

This clinical trial is studying how to reduce the number of unnecessary medications taken by patients on hemodialysis (HD), a treatment for those with end-stage kidney disease. HD patients typically take around 19 medications each day, and research shows that many of these medications may not be suitable for them. The goal of the study is to test new tools that can help doctors identify and stop the use of nine specific medications that are often prescribed but may not be effective or safe for HD patients. By doing this, the researchers hope to lower the number of medications patients take and improve their overall health.

To participate in this trial, individuals must be at least 18 years old, have been receiving outpatient hemodialysis treatment for at least three months, and be able to read and understand English to give their consent. Participants can expect to help improve medication practices at HD centers across Canada, which may lead to better health outcomes and fewer side effects from medications. This trial is currently recruiting participants and aims to make significant changes in how medications are prescribed to HD patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 18+ years
  • Have been receiving outpatient HD treatment at one of the four study sites for at least the past three months
  • Able to read and understand English and provide consent
  • Exclusion Criteria:
  • - Acute starts to HD

About University Health Network, Toronto

University Health Network (UHN), based in Toronto, is a leading academic health sciences center dedicated to advancing patient care through innovative research and education. As a prominent sponsor of clinical trials, UHN integrates cutting-edge scientific discoveries with clinical practice, facilitating the development of new therapies and treatment modalities. With a commitment to improving health outcomes, UHN collaborates with a diverse network of researchers, healthcare professionals, and industry partners, fostering an environment that prioritizes patient safety and ethical standards in clinical research. Through its extensive resources and expertise, UHN plays a pivotal role in transforming healthcare and enhancing the quality of life for patients both locally and globally.

Locations

Toronto, Ontario, Canada

Halifax, Nova Scotia, Canada

Vancouver, British Colombia, Canada

Winnipeg, Manitoba, Canada

Patients applied

0 patients applied

Trial Officials

Marisa Battistella, PharmD

Principal Investigator

University Health Network, Toronto

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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