Treatment for Patients With Chronic Post-Concussion Symptoms
Launched by UNIVERSITY OF CALIFORNIA, LOS ANGELES · Nov 28, 2018
Trial Information
Current as of May 17, 2025
Unknown status
Keywords
ClinConnect Summary
Participants with concussion will participate in six, home-based interventions designed to treat cognitive-behavioral factors that are maintaining their symptoms. The investigators hypothesize that the prolonged PC symptoms are in part due to disruption of autonomic nervous system function post-injury as well as exacerbation by the psychological response to the injury. This hypothesis is based on evidence showing that PC symptoms, including headache, fatigue, dizziness, and heightened anxiety overlap with upregulated sympathetic activity and elevated levels of salivary cortisol. There is ev...
Gender
ALL
Eligibility criteria
- Inclusion criteria for patients:
- • Between the ages of 13-25
- • Diagnosed with a concussion or mild traumatic brain injury by a physician
- • Currently experiencing post-concussive symptoms for at least two months after their injury but no longer than 9 months.
- • Fluent English speaker
- Exclusion Criteria:
- • History of/or comorbid neurological conditions that might affect performance (including history of stroke, seizure disorder, moderate to severe traumatic brain injury, anoxia)
- • Severe cardiovascular conditions.
- • History of psychosis and current substance abuse or dependence.
- • Current severe symptoms of depression and/or anxiety.
- Additional Exclusion Criteria for Controls:
- • \* No history of concussion in the past year.
About University Of California, Los Angeles
The University of California, Los Angeles (UCLA) is a prestigious academic institution renowned for its commitment to research and innovation in the biomedical field. As a clinical trial sponsor, UCLA leverages its cutting-edge facilities, expert faculty, and collaborative environment to advance medical knowledge and improve patient care. The university is dedicated to conducting rigorous clinical research that adheres to the highest ethical standards, aiming to translate scientific discoveries into effective therapies and interventions. Through its diverse array of clinical trials, UCLA seeks to address critical health challenges while fostering the development of future healthcare leaders.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Los Angeles, California, United States
Patients applied
Trial Officials
Robert Asarnow, PhD
Principal Investigator
University of California, Los Angeles
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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