Entropy and Surgical Pleth Index Guided Closed Loop Target Controlled Infusion Total Intravenous Anesthesia With Propofol

Launched by KVG MEDICAL COLLEGE AND HOSPITAL · Dec 11, 2018

Keywords

ClinConnect Summary

Monitoring of Adequacy of Anesthesia using Entropy and Surgical pleth index to guide total intravenous anesthesia is more effective to maintain depth of anesthesia compared with target controlled infusion with open systems, it is unclear what driver and variables to achieve this goal be more physiological; in the literature doesn´t exist studies showing that the closed-loop system for hypnotic is better than the controlled algorithm based pharmacokinetic models and open loop system (target controlled infusion-TCI) to maintain anesthetic depth. Thus, a system was designed for intravenous ane...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Older than 18 years
• • Scheduled for noncardiac surgery elective low-risk or intermediate risk. -Expected surgery time greater than 1 hour
• • Procedure requiring general anesthesia
• • Classification of the American Society of Anesthesiologists (ASA) as I,II, lll
• Exclusion Criteria:
• • Pregnant women
• • Surgery scheduled urgent or emergency
• • Personal history of allergy to eggs or any other part of propofol
• • Personal history of abnormalities or congenital or acquired cognitive sequels: infantile cerebral palsy, Down syndrome, cerebral ischemic disease, traumatic brain injury, brain tumor, autism.
• • Chronic use of benzodiazepines or antipsychotics
• • A patient who does not consent to participate in the study prior to surgery or before randomization
• • Need for anesthetic or analgesic blockade before surgery peripheral nerve