First Real-world Data on Unresectable Stage III NSCLC Patients Treated With Durvalumab After Chemoradiotherapy
Launched by ASTRAZENECA · Jan 8, 2019
Trial Information
Current as of May 14, 2025
Completed
Keywords
ClinConnect Summary
This is a non-interventional/observational study including NSCLC unresectable Stage III patients treated with durvalumab. Patient selection and retrospective data collection will be from participating countries: Australia, Belgium, Israel, Netherlands, Norway France, Germany, Italy, Switzerland, Spain
Chart abstractions will occur at specified intervals up to five years after the patient had the first dose of durvalumab. A target of four (maximum five) chart extractions is anticipated for each participant. Dates may be adjusted based on local market ethics processes or patient enrolment.
...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Written informed consent or any locally required authorisation obtained from the patient prior to performing any protocol-related procedures
- • Age ≥ 18 years at time of study entry or adult according to each country regulations for age of majority
- • Patients must have histologically or cytologically documented diagnosis of NSCLC with a locally advanced, or locally recurrent, unresectable (stage III) disease (according to American Joint Committee on Cancer \[AJCC\] lung cancer edition 7 or 8)
- • Patients must have been enrolled in one of the durvalumab EAPs Patients must have been treated with at least one dose of durvalumab within the EAP prior to the study entry and between start of EAP in the country, from September 2017 or later up to end of EAP enrolment or MA + three months (estimated as maximum to 30 December 2018) (whichever occurs earlier).
- • Patients who die during the EAP are eligible to enter in the study when local laws allow for a consent waiver, if all other inclusion/exclusion criteria are met.
- Exclusion Criteria:
- • -Patients treated with durvalumab in clinical studies prior to the index date (first dose of durvalumab received within the EAP).
About Astrazeneca
AstraZeneca is a global biopharmaceutical company dedicated to the discovery, development, and commercialization of innovative medicines across various therapeutic areas, including oncology, cardiovascular, respiratory, and autoimmune diseases. With a strong commitment to scientific research and patient-centric solutions, AstraZeneca leverages cutting-edge technology and a robust pipeline to address unmet medical needs. The company collaborates with healthcare professionals, academic institutions, and other organizations to advance clinical trials and deliver transformative therapies, aiming to improve health outcomes and enhance the quality of life for patients worldwide.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Brasschaat, , Belgium
Gent, , Belgium
Hasselt, , Belgium
Liège, , Belgium
Aviano, , Italy
Reggio Emilia, , Italy
Varese, , Italy
Milano, , Italy
Manchester, , United Kingdom
Roeselare, , Belgium
Yvoir, , Belgium
Napoli, , Italy
Padova, , Italy
Nijmegen, , Netherlands
Liege, , Belgium
Erlangen, , Germany
Camperdown, , Australia
Lille, , France
Toulouse, , France
Bari, , Italy
Breda, , Netherlands
Rotterdam, , Netherlands
Brussels, , Belgium
Aalst, , Belgium
Rouen Cedex, , France
Hamburg, , Germany
Haifa, , Israel
Holon, , Israel
Arezzo, , Italy
Pavia, , Italy
Udine, , Italy
Arnhem, , Netherlands
Groningen, , Netherlands
Heerlen, , Netherlands
Arendal, , Norway
Ottignies, , Belgium
Utrecht, , Netherlands
Bethune Cedex, , France
Bochum, , Germany
Kaiserslautern, , Germany
Oldenburg, , Germany
Paderborn, , Germany
Drammen, , Norway
Tromso, , Norway
Stoke On Trent, , United Kingdom
Melbourne, , Australia
La Roche Sur Yon Cedex 9, , France
Nottingham, , United Kingdom
Amsterdam, , Netherlands
Ramat Gan, , Israel
Muret, , France
Lyon Cedex 08, , France
Nahariya, , Israel
Chur, , Switzerland
Sint Niklaas, , Belgium
Regensburg, , Germany
Box Hill, , Australia
Sint Truiden, , Belgium
Ashkelon, , Israel
Jerusalem, , Israel
Ieper, , Belgium
Halle (Saale), , Germany
Lecce, , Italy
Brest Cedex, , France
Rennes Cedex 9, , France
Perugia, , Italy
Rozzano, , Italy
Bruxelles, , Belgium
Saint Priest En Jarez, , France
Firenze, , Italy
Birmingham, , United Kingdom
Modena, , Italy
Cardiff, , United Kingdom
Recklinghausen, , Germany
Petah Tikva, , Israel
Poole, , United Kingdom
Muenchen, , Germany
Lausanne, , Switzerland
Roma, , Italy
Clayton, , Australia
Elizabeth Vale, , Australia
Ronse, , Belgium
Nazareth, , Israel
Terni, , Italy
Amersfoort, , Netherlands
London, , United Kingdom
Bayonne, , France
Nancy, , France
Genova, , Italy
Berlin, , Germany
Poitiers, , France
Essen, , Germany
Bobigny Cedex, , France
Paris Cedex 10, , France
Alessandria, , Italy
Hertogenbosch, , Netherlands
Sora, , Italy
Aix En Provence, , France
Würselen, , Germany
Zutphen, , Netherlands
Mons, , Belgium
Parma, , Italy
Pisa, , Italy
Nimes, , France
Treviglio, , Italy
Monza, , Italy
Clermont Ferrand, , France
Limoges, , France
Joondalup, , Australia
Murdoch, , Australia
Wollongong, , Australia
Alkmaar, , Netherlands
Ede, , Netherlands
Eindhoven, , Netherlands
Ancona, , Italy
Esslingen, , Germany
Karlsruhe, , Germany
Maastricht, , Netherlands
Colchester, , United Kingdom
Pierre Benite Cedex, , France
Le Mans Cedex, , France
Meldola, , Italy
Bolzano, , Italy
Malvern, , Australia
Beer Sheva, , Israel
Mirano, , Italy
Coffs Harbour, , Australia
Bouge, , Belgium
La Rochelle Cedex, , France
Antony, , France
Creteil Cedex, , France
Paris, , France
Douglas, , Australia
Hobart, , Australia
Wendouree, , Australia
Fürth, , Germany
Rimini, , Italy
Catanzaro, , Italy
Brescia, , Italy
Dresden, , Germany
Frankston, , Australia
Bedford Park, , Australia
Bendigo, , Australia
Westmead, , Australia
Pau Cedex, , France
St Leonards, , Australia
Campbelltown, , Australia
Rostock, , Germany
Messina, , Italy
Kfar Saba, , Israel
Liverpool, , Australia
Immenhausen, , Germany
Marseille, , France
Ravenna, , Italy
Rionero In Vulture (Pz), , Italy
Paris Cedex 14, , France
Subiaco, , Australia
Den Haag, , Netherlands
Avignon Cedex 09, , France
Tours Cedex, , France
Saint Quentin Cedex, , France
Grenoble, , France
Montpellier, , France
Marseille Cedex 20, , France
Dendermonde, , Belgium
Loverval, , Belgium
Orange, , Australia
Kingswood, , Australia
Ballarat, , Australia
Bankstown, , Australia
Bentleigh East, , Australia
Bowral, , Australia
Canberra, , Australia
Hamlyn Terrace, , Australia
Hervey Bay, , Australia
Rockhampton, , Australia
Traralgon, , Australia
Tugun, , Australia
Warrnambool, , Australia
Braine L'alleud, , Belgium
Herstal, , Belgium
Heusden Zolder, , Belgium
Kuringen, , Belgium
Abbeville, , France
Albi Cedex 09, , France
Beziers, , France
Bordeaux, , France
Boulogne Billancourt Cedex, , France
Carcassonne Cedex, , France
Chauny, , France
Colmar, , France
Contamine Sur Arve, , France
Dijon Cedex, , France
Gap Cedex, , France
Levallois Perret, , France
Libourne Cedex, , France
Lorient, , France
Macon, , France
Metz Tessy, , France
Morlaix Cedex, , France
Nîmes, , France
Paris Cedex 5, , France
Perigueux, , France
Perpignan, , France
Saint Nazaire Cedex, , France
Saint Aubin Lès Elbeuf, , France
Tarbes, , France
Toulon Cedex 9, , France
Valence, , France
Vantoux, , France
Villefranche Sur Saône Cedex, , France
Bremen, , Germany
Georgsmarienhuette, , Germany
Gütersloh, , Germany
Kempten, , Germany
Münnerstadt, , Germany
Tel Aviv, , Israel
Feltre, , Italy
Imola, , Italy
L'aquila (Aq), , Italy
La Spezia, , Italy
Lido Di Camaiore, , Italy
Pistoia, , Italy
Trieste, , Italy
Verona, , Italy
Hilversum, , Netherlands
Leiden, , Netherlands
Nieuwegein, , Netherlands
Oslo, , Norway
Altdorf, , Switzerland
Bulach, , Switzerland
Fribourg, , Switzerland
Geneva, , Switzerland
Neuchâtel, , Switzerland
Furth, , Germany
Saint Aubin Les Elbeuf, , France
Villefranche Sur Saone Cedex, , France
Gutersloh, , Germany
Munnerstadt, , Germany
Wurselen, , Germany
Neuchatel, , Switzerland
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials