The Effect Of Vitamin D Replacement Therapy On Serum Leptin And Follicular Growth Pattern In Women With Resistant Polycystic Ovary
Launched by CAIRO UNIVERSITY · Jan 13, 2019
Trial Information
Current as of May 27, 2025
Unknown status
Keywords
ClinConnect Summary
The study included 100 female diagnosed with polycystic ovary syndrome diagnosed by by presence of 2 out of 3 criteria (according to ESHRE/ASRM in Rotterdam in 2003): oligoovulation and/or an ovulation , excess androgen activity (clinical or biochemical) and polycystic ovaries (by pelvic ultrasound "vaginal route").They were classified into 2 groups: Study group included 50 women will receive 300.000 I.U single dose of Vitamin D intramuscular injection (Memphis company) , and in the next menstrual cycle induction done by clomiphen citrate 100mg daily for 5 days starting from third day of me...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • 1- BMI: more than 25.0 kg/m2
- • 2- PCO was diagnosed by presence of 2 out of 3 criteria (according to ESHRE/ASRM in Rotterdam in 2003)
- • 1. oligoovulation and/or an ovulation
- • 2. excess androgen activity (clinical or biochemical)
- • 3. polycystic ovaries (by pelvic ultrasound "vaginal route")
- • 3- Anovulatory patient resistant to induction with clomiphene citrate alone
- Exclusion Criteria:
- • -1) BMI: more than 35.0 kg/m2
- • 2) Infertile women due to any factor other than PCO
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, , Egypt
Patients applied
Trial Officials
Ahmed Maged
Principal Investigator
Professor
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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