Non-invasive Ventilation vs Oxygen Therapy After Extubation Failure

Launched by FUNDACIÓN PARA EL FOMENTO DE LA INVESTIGACIÓN SANITARIA Y BIOMÉDICA DE LA COMUNITAT VALENCIANA · Feb 4, 2019

Keywords

ClinConnect Summary

Patients. Medical and surgical patients admitted to intensive care unit with 18 years of age or older in weaning from their first episode of mechanical ventilation for more than 24 hours were included. Patients with structural neurological disorder, acute toxic-metabolic neurological encephalopathy with neurological deficit \[estimated by a Glasgow Coma Score \<14 points\] at the time of weaning, neuromuscular disease, chronic obstructive pulmonary disease receiving non-invasive ventilation, limitation of life support therapy during their admission, tracheostomized patients, spinal cord inj...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Medical and surgical ICU patients with 18 years of age or older
• • First episode of mechanical ventilation for more than 24 hours
• Exclusion Criteria:
• • Structural neurological disorder
• • Acute toxic-metabolic neurological encephalopathy with neurological deficit \[estimated by a Glasgow Coma Score (GCS) \<14 points\] at the time of weaning
• • Neuromuscular disease
• • Chronic obstructive pulmonary disease (COPD) receiving NIV
• • Limitation of life support therapy during their admission
• • Tracheostomized patients
• • Spinal cord injuries
• • Scheduled surgical procedure during the 48 hours following extubation
• • Intensive care unit readmission
• • Transfer to another centre
• • Contraindication to non-invasive mechanical ventilation