Different Volatile Anaesthetics and the Depth of Long Term ICU Sedation

Launched by RUHR UNIVERSITY OF BOCHUM · Feb 28, 2019

Keywords

ClinConnect Summary

The study was approved by the appropriate Institutional Review Board. Thirty ASA II-IV patients, undergoing elective or emergency surgery under general anaesthesia were included and randomized into three equal groups: ISO, SEVO or DES. We used MIRUS, a gas delivery system with a VA reflector, just like AnaConDa, that can be paired with common ICU ventilators. Additionally, MIRUS features the unique ability to maintain the end-tidal concentration (etVA) in target by automatically adjusting the delivery rate. Every 8 hours, the RASS was assessed by the nurse. The log of the EEG-Narcotrend Ind...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Signing of the informed consent document (patient or relatives).
• • Patient age 18 years or older.
• • ASA I-III
• Exclusion Criteria:
• • ASA IV patients
• • Epidural or spinal analgesia
• • Allergy or known hypersensitivity to any of the study drugs
• • Patients with known or suspected genetic susceptibility to malignant hyperthermia
• • Previous participation in this trial
• • Participation in another clinical trial within 4 weeks prior to selection.
• • Pregnant women