SNAKES Trial: Jelly Snakes to Prevent PONV in Kids After ENT Surgery

Launched by PROF. THOMAS ENGELHARDT · Mar 14, 2019

Keywords

ClinConnect Summary

Primary Hypothesis Chewing large jelly snakes will significantly reduce the development of postoperative vomiting in paediatric patients in the first 6 hours after volatile anaesthetic-based general anaesthesia for tonsillectomies +/- adenoidectomies.

Secondary Hypotheses:

1. Jelly snakes will reduce the incidence of nausea in the first 6 hours after tonsillectomy +/- adenoidectomy surgery
2. Jelly snakes will reduce rescue treatments for PONV in the first 6 hours
3. Jelly snakes will reduce the incidence of PONV in the first 24 hours or up until discharge in case of tonsillectomies (what...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Volatile anaesthetic-based general anaesthesia
• • Written informed parental consent
• • Elective tonsillectomy +/- adenoidectomy (+/- myringotomy, EUA ear, grommets or cautery of inferior turbinates')
• Exclusion Criteria:
• • Plan to use muscle relaxant
• • Plan to use topical lignocaine on the vocal cords intraoperatively
• • Contraindication to chewy jelly snakes or any of their components e.g. known allergy to any of the ingredients of the chewy jelly snakes or impaired pharyngeal/oesophageal function (e.g. bulbar palsy, achalasia), children with diabetes and vegetarian children
• • Contraindication to any protocolised anti-emetic drug (prophylaxis, intervention or rescue)
• • Parents/guardians or children who, in the opinion of the investigator, may be unable to understand or give informed consent will be excluded from the study.