The Efficacy and Molecular Mechanism of Botulinum Toxin in the Reduction of Breast Reduction Mammoplasty Scar Formation

Launched by HENRY FORD HEALTH SYSTEM · Mar 20, 2019

Keywords

ClinConnect Summary

Breast reduction mammoplasty is an increasingly popular procedure in this country due to not only the perceived cosmetic benefit of the procedure but additionally the improvement in musculoskeletal pain, headaches, sleeping difficulties, breathing, depression, self-esteem, and eating disorders. Despite these benefits, outcome satisfaction the typical inverted-T scar of the Wise pattern reduction has been limited by the resulting scar formation on the breast tissue. One study demonstrated that although 86% of patients were highly satisfied with their surgery, 65% were dissatisfied with their...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Undergoing breast reduction surgery
• • 2. Does not meet any exclusion criteria
• • 3. Female
• • 4. \>18 years old
• • 5. Willing to participate in study
• Exclusion Criteria:
• • 1. Allergy to botulinum toxin
• • 2. Currently pregnant or breast feeding
• • 3. Myasthenia gravis
• • 4. Lambert-Eaton Myasthenic Syndrome
• • 5. Amyopathic Lateral Sclerosis
• • 6. Previous injection of botulinum toxin in the chest area within 6 months prior to enrollment
• • 7. History of keloid or hypertrophic scar
• • 8. History of previous breast surgery with scar affecting inframammary skin
• • 9. Male Sex
• • 10. Refusal to participate in the study
• • 11. Unable to make follow up appointments up to 6 months
• • 12. Less than 18 years of age
• • 13. History of radiation to the breast