Paracetamol Route in Palliative Care Patients (PARASCIVPALLIA)

Launched by UNIVERSITY HOSPITAL, CAEN · May 7, 2019

Keywords

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients ≥ 18 years old, hospitalized
• • Patients in a palliative care situation
• • Patients having an intravenous device with the presence of a venous reflux (be implantable venous site, picc-line, central track)
• • Patients having a spontaneous pain, not related to care, with a numeric pain rate scale (NPRS) \> 3/10 or have a systematic prescription of paracetamol in the usual treatment
• • Patients able to do an auto-evaluation of their pain by NPRS
• • No contraindications of paracetamol
• • No contraindications of alternative antalgic (low opioids, strong opioids, Non-steroidal anti-inflammatory)
• • Possibility to not take paracetamol in the previous 24 hours before inclusion
• • Patients with a blood test dating back less than 7 days, with no severe renal or hepatic failure
• • Patients related with a French social security regime
• • Patients accept to participate in the study, with written consent.
• Exclusion Criteria:
• • Patients under legal protection
• • Patients who participate in another study less than 30 days before
• • Patients weighing less than 50 kg
• • Patients having a contraindication to subcutaneous route
• • Pregnant or breastfeeding woman
• • Patients who having a paracetamol administration less than 24 hours before the beginning of the inclusion
• • Patients who having a low opioid less than 2 hours before or a strong opioid less than one hour before the beginning of administration of paracetamol
• • Patients having a fever
• • No possibility of communication