The Anti-oxidant Effects of N-Acetylcysteine in Chronic Obstructive Pulmonary Disease (COPD)
Launched by SIRIRAJ HOSPITAL · May 16, 2019
Trial Information
Current as of June 17, 2025
Completed
Keywords
ClinConnect Summary
No description provided
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Eligible stable COPD patients who are currently treated with only short-acting bronchodilator (salbutamol or fenoterol/ipratropium bromide) or long-acting bronchodilator (LABA or LAMA) or inhaled corticosteroids/LABA
- • Pre-bronchodilator FEV1 ≥ 80% and \< 80% predicted
- • Current or ex-smokers (≥ 10 pack year)
- Exclusion Criteria:
- • Concomitant with active and old pulmonary TB, lung cancer, bronchiectasis, lung fibrosis, destroyed lung and other malignancies
- • Recent acute coronary syndrome (within 12 weeks)
- • Cerebrovascular disease without neurological recovery
- • Cognitive impairment
- • Recent acute exacerbation of COPD (within 4 weeks)
- • Recent respiratory viral infection (within 4 weeks)
- • Could not provide adequate sputum specimens
- • Develop worsening of COPD symptoms during sputum induction
- • Could not provide informed consent
About Siriraj Hospital
Siriraj Hospital, a leading healthcare institution in Thailand, is renowned for its commitment to advancing medical research and improving patient care through clinical trials. Affiliated with Mahidol University, Siriraj Hospital integrates cutting-edge technology and innovative methodologies to conduct a wide range of clinical studies across various medical disciplines. The institution emphasizes ethical standards and patient safety, fostering collaborations with national and international research entities to contribute to the global medical community. With a focus on translating research findings into practical applications, Siriraj Hospital aims to enhance treatment options and health outcomes for diverse populations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Bangkok, , Thailand
Patients applied
Trial Officials
Kittipong Maneechotesuwan, MD., PhD.
Principal Investigator
Siriraj Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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