Piroxicam Premedication for Postendodontic Pain in Non-vital Mandibular Molars
Launched by CAIRO UNIVERSITY · Jun 25, 2019
Trial Information
Current as of May 29, 2025
Unknown status
Keywords
ClinConnect Summary
* Patients will be clinically and radiographically examined and their eligibility will be assessed. Eligible patients will be treated in one visit.
* Patients will be randomly assigned to one of 2 groups: experimental group (premedication with 20 mg of piroxicam) and the control group (premedication with placebo). Each participant will receive a standard inferior alveolar nerve block injection. After endodontic treatment, patients will be given postoperative instructions and informed, in case of pain, to receive ibuprofen 200 mg as rescue medication.
* Postendodontic pain intensity and inci...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Patients aging between 18-50 years old
- • 2. Patients with mandibular molar with non-vital pulp.
- • 3. Systemically- healthy patients (ASA I or II).
- • 4. Patients who agree to attend for recall appointments and provide a written consent.
- Exclusion Criteria:
- • 1. Pregnant or lactating female patients.
- • 2. Patients allergic to piroxicam.
- • 3. History of peptic ulceration.
- • 4. Periapical abscess, fistula.
- • 5. Non-restorable teeth.
- • 6. Moderate or severe marginal periodontitis i.e. pocket probe\>3mm.
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Asmaa FE Mohamed, B.D.S
Principal Investigator
Cairo University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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