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Search / Trial NCT03998826

Piroxicam Premedication for Postendodontic Pain in Non-vital Mandibular Molars

Launched by CAIRO UNIVERSITY · Jun 25, 2019

Trial Information

Current as of May 29, 2025

Unknown status

Keywords

Piroxicam Postendodontic Pain Analgesic Intake

ClinConnect Summary

* Patients will be clinically and radiographically examined and their eligibility will be assessed. Eligible patients will be treated in one visit.
* Patients will be randomly assigned to one of 2 groups: experimental group (premedication with 20 mg of piroxicam) and the control group (premedication with placebo). Each participant will receive a standard inferior alveolar nerve block injection. After endodontic treatment, patients will be given postoperative instructions and informed, in case of pain, to receive ibuprofen 200 mg as rescue medication.
* Postendodontic pain intensity and inci...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Patients aging between 18-50 years old
  • 2. Patients with mandibular molar with non-vital pulp.
  • 3. Systemically- healthy patients (ASA I or II).
  • 4. Patients who agree to attend for recall appointments and provide a written consent.
  • Exclusion Criteria:
  • 1. Pregnant or lactating female patients.
  • 2. Patients allergic to piroxicam.
  • 3. History of peptic ulceration.
  • 4. Periapical abscess, fistula.
  • 5. Non-restorable teeth.
  • 6. Moderate or severe marginal periodontitis i.e. pocket probe\>3mm.

About Cairo University

Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.

Locations

Patients applied

0 patients applied

Trial Officials

Asmaa FE Mohamed, B.D.S

Principal Investigator

Cairo University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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