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Search / Trial NCT04004676

Ketone Supplementation, Glycogen Replenishment and Time Trial Performance Following Glycogen Lowering Exercise

Launched by WESTERN UNIVERSITY, CANADA · Jun 27, 2019

Trial Information

Current as of June 09, 2025

Unknown status

Keywords

Ketones Glycogen Replenishment Exercise Performance

ClinConnect Summary

Carbohydrates (starches \& sugars) are important muscle fuel for exercise at moderate to high intensities. Low glycogen content (stored form of carbohydrates in the body) is associated with fatigue. Thus, greater initial glycogen content has been associated with better performance not only in high intensity intermittent sports, but also in prolonged endurance sports. Dose-response studies have determined that ingestion of 1.2 g·kg-1·h-1 of CHO is the appropriate acute recovery dose to optimize glycogen repletion, with no apparent benefit at higher doses. Protein in combination with CHO has ...

Gender

MALE

Eligibility criteria

  • Inclusion Criteria:
  • In order to be eligible to participate in this study you must be a healthy male or female exercise trained individual (at least 1y training experience - at least 3x week), aged 18-40 years.
  • Exclusion Criteria:
  • have not involved been involved in regular exercise (at least 3x week for at least the past year)
  • Have symptoms or take medication for respiratory, cardiovascular, metabolic, neuromuscular disease
  • Use any medications with side effects of dizziness, lack of motor control, or slowed reaction time
  • Are taking part in another research study
  • For women, if you are pregnant or become pregnant during the study.
  • Have a history of concussion/head injuries.
  • Have an excessive alcohol intake (\>2 drinks/day)
  • Are a smoker

About Western University, Canada

Western University, located in Canada, is a leading research institution committed to advancing healthcare through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university harnesses the expertise of its faculty and research teams to conduct high-quality studies that address pressing medical challenges. Western University is dedicated to fostering a culture of ethical research practices, ensuring participant safety, and generating impactful findings that contribute to evidence-based medicine and improve patient outcomes. Through its robust infrastructure and commitment to excellence, Western University plays a vital role in the field of clinical research.

Locations

London, Ontario, Canada

Patients applied

0 patients applied

Trial Officials

Peter Lemon, PhD

Principal Investigator

Western Universiy

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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