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Search / Trial NCT04018157

Single Bolus Dose of Ketodex Versus Ketofol For Prevention Of Emergence Agitation In Adults Undergoing Nasal Surgeries

Launched by ZAGAZIG UNIVERSITY · Jul 11, 2019

Trial Information

Current as of May 23, 2025

Completed

Keywords

Ketodex, Ketofol , Agitation , Nasal Surgery

ClinConnect Summary

The incidence of emergence agitation (EA) after nasal surgeries is relatively high , it is reported to be 68% (1).The precise mechanism is not known. Awake extubation after nasal surgeries is preferred as the airway may be contaminated by blood , and the nasal airway may be blocked by surgical packs that causes sense of suffocation. Awake extubation and nasal pack is a trigger to emergence agitation(2).

emergence agitation (EA) is harmful to the patient and the staff, it Characterized by disorientation, confusion, abnormal violent movement that may result in serious complication and morbid...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patient acceptance.
  • Both gender.
  • Age (21-60) years old.
  • patient with Body Mass Index (BMI) (25-35kg/m²).
  • American Society of Anesthesiologist (ASA) I / II
  • Adult patient scheduled to elective nasal surgeries
  • Exclusion Criteria:
  • - Patient with difficult airway (mallampati III,IV).
  • Altered mental status (psychiatric and anxiety disorder).
  • Post traumatic stress disorders.
  • History of allergy to study drugs.
  • Patient on sedative or hypnotic medication.
  • Patients with chronic pain or on painkiller.
  • Patients with severe hepatic or kidney impairment.
  • Patients having a history of thyrotoxicosis, hypertension, cardiac , chest or neurological disease.
  • Patient receiving B agonist.
  • Pregnant or breast feeding female.

About Zagazig University

Zagazig University, a prominent educational and research institution located in Egypt, plays a pivotal role in advancing medical knowledge and promoting health innovations through its clinical trials. With a commitment to excellence in research, the university leverages its diverse expertise and state-of-the-art facilities to conduct rigorous clinical studies that aim to improve patient care and outcomes. By fostering collaboration among multidisciplinary teams, Zagazig University contributes significantly to the global medical community, ensuring that its clinical trials adhere to the highest ethical standards and regulatory requirements.

Locations

Zagazig, Elsharkia, Egypt

Patients applied

0 patients applied

Trial Officials

Olfat Amin, M.D

Principal Investigator

Faculty of medicine, Zagazig university

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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