Premature Atherosclerosis in Systemic Lupus Erythematosus
Launched by PEKING UNION MEDICAL COLLEGE HOSPITAL · Jul 29, 2019
Trial Information
Current as of May 22, 2025
Unknown status
Keywords
ClinConnect Summary
Accelerated atherosclerosis is a major complication of systemic lupus erythematosus (SLE), and it leads to increased cardiovascular morbidity and mortality in patients with SLE. Prevention and intervention of premature atherosclerosis is beneficial for prognosis and survival of patients with SLE.
The primary aim of this study was to investigate the natural progress of carotid intima media thickness (CIMT) in 5 years, and examine the risk factors for progression of CIMT and atherosclerotic plaques based on a Chinese SLE cohort. The secondary aims of the study were to investigate progression...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age≥18 years
- • Fulfillment of clinical classification criteria of SLE (four or more 1997 American College of Rheumatology classification criteria)
- • Provision of signed written informed consent
- Exclusion Criteria:
- • Clinically overt coronary artery disease
- • A history of cardiovascular disease (previous stroke, heart failure, myocardial infarction, angina, or symptomatic PAD)
- • Malignancy
- • Pregnant/lactating women
About Peking Union Medical College Hospital
Peking Union Medical College Hospital (PUMCH) is a prestigious medical institution and a leading research facility located in Beijing, China. Affiliated with the Chinese Academy of Medical Sciences, PUMCH is renowned for its commitment to advancing healthcare through innovative clinical research and high-quality patient care. The hospital plays a pivotal role in the development and execution of clinical trials across various medical disciplines, focusing on improving treatment outcomes and enhancing medical knowledge. With a multidisciplinary team of experts and state-of-the-art facilities, PUMCH is dedicated to contributing to global health advancements and fostering collaborations in the medical research community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Beijing, Beijing, China
Patients applied
Trial Officials
Shuyang Zhang, MD
Study Chair
Peking Union Medical College Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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