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Search / Trial NCT04091802

Effect of Monolayer Versus Multilayer Leucocyte-Platelet Rich Fibrin (L-PRF) in Interdental Papillary Reconstruction

Launched by AIN SHAMS UNIVERSITY · Sep 14, 2019

Trial Information

Current as of June 05, 2025

Completed

Keywords

Interdental Papilla Reconstruction Leucocyte Platelet Rich Fibrin (L Prf)

ClinConnect Summary

A total of 20 patients will be selected who are caring about esthetics and concerned to go through the management of eradication of "black triangles" by interdental papillae reconstruction in esthetic zone and systemically free with Nordland's class I or II and The vertical distance from the interdental contact point to the crest of the interdental bone is ≥ 6 mm as measured by bone sounding, A band of keratinized tissue should be present around the test teeth ≥ 2 mm, Gingival biotype of the area to be treated is ≥ 2 mm in thickness.

The study protocol will be explained in details to all p...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Patients diagnosed with black triangles. 2. Both genders aged from 18-40 years. 3. Patients should be systemically free. 4. Patients with Nordland's class I or II. Nordland and Tarnow classified the interdental papilla loss; the classification is based on three anatomic landmarks: the contact point interdentally, the coronal level of the CEJ interproximally and the facial apical level of the cemento-enamel junction (CEJ). \[Nordland WP, et al, 1998\] Four classes were identified
  • Normal: The interdental papilla fills up the whole embrasure to the interproximal contact point.
  • Class I: Presence of the tip of the papilla between interdental contact point and the interproximal CEJ.
  • Class II: Presence of the tip of the papilla at the interproximal CEJ or apical to it but still coronal to the facial CEJ.
  • Class III: Presence of the tip of papilla at similar plane with the labial CEJ or apical to it.
  • 5. The vertical distance from the interdental contact point to the crest of the interdental bone is ≥ 6 mm as measured by bone sounding.
  • 6. A band of keratinized tissue should be present around the test teeth ≥ 2 mm. 7. Gingival biotype of the area to be treated is ≥ 2 mm in thickness.
  • Exclusion Criteria:
  • 1. Acute periapical lesion.
  • 2. moderate to severe form of periodontitis.
  • 3. Pregnancy and lactation.
  • 4. parafunctional habits.
  • 5. Smoking, alcoholics or drug abusers.
  • 6. Teeth with interdental spacing, rotation or inclination or crowding.
  • 7. Vulnerable group of patients.

About Ain Shams University

Ain Shams University, established in Cairo, Egypt, is a prestigious higher education institution renowned for its commitment to academic excellence and research innovation. As a clinical trial sponsor, the university leverages its extensive resources and expertise in various medical and scientific disciplines to advance healthcare through rigorous research initiatives. With a focus on ethical practices and adherence to regulatory standards, Ain Shams University aims to contribute to the development of new therapies and improve patient outcomes, fostering collaboration among researchers, healthcare professionals, and industry partners in the pursuit of medical advancements.

Locations

Patients applied

0 patients applied

Trial Officials

Nivine H. kheir el den, professor

Study Chair

faculty of dentistry- ain shams university

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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