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Search / Trial NCT04096677

Effects of Hysteroscopy and Transvaginal Surgery on Reproductive Prognosis in Patients With Post Cesarean Scar Defect

Launched by FIRST AFFILIATED HOSPITAL, SUN YAT-SEN UNIVERSITY · Sep 18, 2019

Trial Information

Current as of June 20, 2025

Unknown status

Keywords

Post Cesarean Scar Defect Hysteroscopy Transvaginal Intervention Endometrial Receptive

ClinConnect Summary

Post cesarean scar defect (PCSD), refers the lower uterine segment form a reservoir-like pouch during healing process after transverse lower uterine segment cesarean section connected with uterine cavity. The pouch has a valve-like effect, obstructing blood drainage and accumulating blood in depression. These causes may lead to a variety of gynecological disturbances, secondary dysmenorrheal and infertility. Some patients can occur some serious obstetric complications, such as cesarean scar pregnancy and even the rupture of uterus during a subsequent pregnancy. At present, the causes and me...

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Patients had a history of transverse lower uterine segment cesarean section;
  • Patients had a previous regular menstruation, while after caesarean section, they occurred prolonged postmentrual bleeding (10-20days)
  • Medication failed(contraceptive pills).
  • Sex hormone test is normal;
  • TVU or hysteroscopy showed a triangular or U-shaped anechoic liquid dark area and on the anterior lower uterine segment in relation to cesarean section scar during menstruation of 7-12 days or hysteroscopic examination showed uterine anterior wall defect like dome changes at isthmus below internal orifice of cervix.
  • Exclusion Criteria:
  • Irregular menstrual cycle before cesarean section
  • Previous placement of an intrauterine contraceptive device
  • Presence of other organic uterine pathology responsible for abnormal uterine bleeding, such as endometrial hyperplasia, polyps or submucosal myomas, cervical cancer, endometrial cancer, etc
  • Existence of endocrine diseases, such as dysfunction of pituitary, ovarian, adrenal gland, and thyroid;
  • Coagulation dysfunction.

About First Affiliated Hospital, Sun Yat Sen University

The First Affiliated Hospital of Sun Yat-sen University is a prestigious medical institution located in Guangzhou, China, renowned for its commitment to advancing healthcare through innovative clinical research and comprehensive patient care. As a leading teaching hospital, it combines clinical excellence with academic rigor, facilitating a wide range of clinical trials across various specialties. The hospital is dedicated to improving health outcomes and contributing to medical knowledge, leveraging its state-of-the-art facilities and a team of highly qualified professionals to conduct high-quality research that adheres to international standards.

Locations

Guangzhou, Guangdong, China

Guangzhou, Guangdong, China

Patients applied

0 patients applied

Trial Officials

Yuqing Chen

Study Chair

The First Affiliated Hospital of SunYetSen University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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