Effect of Platelet-Rich Plasma Biomembrane on Enhancing Bone Regeneration Following Endodontic Surgery
Launched by ALEXANDRIA UNIVERSITY · Sep 27, 2019
Trial Information
Current as of April 25, 2025
Completed
Keywords
ClinConnect Summary
15 healthy patients of both genders, between 20 and 45 years of age, presenting with 22 anterior/premolar teeth in need of endodontic surgery were recruited. Teeth presented with failed non-surgical root canal therapy and periapical radiolucency of ≥ 1cm in size. Patients were randomly divided following surgery into two groups, with 11 teeth each.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Healthy patients.
- • 2. Selected tooth with previous root canal therapy failure and in need of endodontic surgery.
- • 3. Existence of a periapical radiographic lesion surrounding the root canal treated tooth, of size ≥ 1 cm.
- • 4. Healthy periodontal condition (probing depth, mobility \& epithelial attachment level are all within normal range).
- Exclusion Criteria:
- • 1. Leaking coronal restoration.
- • 2. Periodontal ligament breakdown and presence of apicomarginal defects.
Trial Officials
salma genena, PhD
Principal Investigator
Alexandria University
About Alexandria University
Alexandria University, a leading academic institution in Egypt, is dedicated to advancing medical research and improving healthcare outcomes through innovative clinical trials. With a strong emphasis on collaboration and interdisciplinary approaches, the university leverages its extensive resources and expertise to conduct rigorous studies that address pressing health challenges. By fostering partnerships with healthcare professionals, industry leaders, and regulatory bodies, Alexandria University aims to contribute to the global body of medical knowledge and enhance the quality of patient care through evidence-based findings.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Alexandria, , Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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