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Search / Trial NCT04109417

Effect of Platelet-Rich Plasma Biomembrane on Enhancing Bone Regeneration Following Endodontic Surgery

Launched by ALEXANDRIA UNIVERSITY · Sep 27, 2019

Trial Information

Current as of April 25, 2025

Completed

Keywords

ClinConnect Summary

15 healthy patients of both genders, between 20 and 45 years of age, presenting with 22 anterior/premolar teeth in need of endodontic surgery were recruited. Teeth presented with failed non-surgical root canal therapy and periapical radiolucency of ≥ 1cm in size. Patients were randomly divided following surgery into two groups, with 11 teeth each.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Healthy patients.
  • 2. Selected tooth with previous root canal therapy failure and in need of endodontic surgery.
  • 3. Existence of a periapical radiographic lesion surrounding the root canal treated tooth, of size ≥ 1 cm.
  • 4. Healthy periodontal condition (probing depth, mobility \& epithelial attachment level are all within normal range).
  • Exclusion Criteria:
  • 1. Leaking coronal restoration.
  • 2. Periodontal ligament breakdown and presence of apicomarginal defects.

Trial Officials

salma genena, PhD

Principal Investigator

Alexandria University

About Alexandria University

Alexandria University, a leading academic institution in Egypt, is dedicated to advancing medical research and improving healthcare outcomes through innovative clinical trials. With a strong emphasis on collaboration and interdisciplinary approaches, the university leverages its extensive resources and expertise to conduct rigorous studies that address pressing health challenges. By fostering partnerships with healthcare professionals, industry leaders, and regulatory bodies, Alexandria University aims to contribute to the global body of medical knowledge and enhance the quality of patient care through evidence-based findings.

Locations

Alexandria, , Egypt

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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