Conservative Management in Patients Diagnosed With Grade 2 or Grade 3 CIN

Launched by FUNDACIÓ INSTITUT DE RECERCA DE L'HOSPITAL DE LA SANTA CREU I SANT PAU · Oct 2, 2019

Keywords

ClinConnect Summary

Follow-up is performed every 4 months with colposcopy, cytology and biopsies. Colposcopy and cytology are performed for all control subjects. The need for biopsy is established according to the colposcopy exam findings to confirm H-SIL or cervical cancer. Follow-up is spaced every 6 months if the cytology and biopsy results indicate L-SIL / ASCUS in agreement with the colposcopic image. HPV tests are performed every 8-12 months. This strategy is maintained until the resolution of the H-SIL.

The conservative management stops if the H-SIL lesion persists after 24 months of follow-up, if the ...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Reproductive age and willing to get pregnant in the future
• • Acceptance of conservative management
• • Commitment to study visits.
• • Colposcopy with zone of transformation (ZT) type 1 or 2 (Unio esco-columnar totally visible) with image compatible with H-SIL and visible in its entirety.
• Exclusion Criteria:
• • Pregnant women
• • Immunosuppression for human immunodeficiency virus (HIV) or iatrogenic type
• • suspicion or diagnosis of Glandular Cell Atipia (ACG), Adenocarcinoma in situ (AIS) or cervical cancer (CC)
• • Provided that inclusion criteria are not met