Prevalence of HPV-associated Eye Infection and Cytokine Levels in Tears From Patients Diagnosed With Pterygium
Launched by CHULALONGKORN UNIVERSITY · Oct 3, 2019
Trial Information
Current as of April 24, 2025
Completed
Keywords
ClinConnect Summary
The main purpose of this study is to evaluate the prevalence of HPV infection in primary and recurrent pterygium and the association of HPV types collecting from conjunctiva swab and urine. The second purpose is to compare a quantity of cytokines including IL-6, IL-18 and growth factor including VEGF found in tears of patients with primary and recurrent pterygium to participants with free of ocular disease Primary hypothesis
- The prevalence of HPV infection in primary pterygium is difference with prevalence in recurrent pterygium patients.
Secondary hypothesis
* Ocular HPV infection has...
Gender
ALL
Eligibility criteria
- • Participants as primary and secondary pterygium group
- Inclusion Criteria:
- • Age above 18 years old
- • presence of pterygium invading the cornea
- Exclusion Criteria:
- • Other ocular inflammation that could affect the results of the study (such as conjunctivitis, keratitis, conjunctival tumor, etc) or would preclude the enrollment for safety reasons
- • Participant without ocular disease Inclusion criteria
- • Age above 18 years old Exclusion criteria
- • Presence of any ocular inflammation diseases
Trial Officials
Ngamjit Kasetsuwan
Principal Investigator
Department of Ophthalmology, Chulalongkorn University
About Chulalongkorn University
Chulalongkorn University, one of Thailand's premier academic institutions, is dedicated to advancing medical research and enhancing healthcare outcomes through innovative clinical trials. With a strong emphasis on collaboration and interdisciplinary approaches, the university leverages its extensive resources and expertise in various medical fields to conduct rigorous scientific investigations. Chulalongkorn University aims to contribute to global health advancements by fostering a culture of excellence in research, education, and community service, ultimately improving patient care and public health standards.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Bangkok, , Thailand
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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