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Search / Trial NCT04117386

Prevalence of HPV-associated Eye Infection and Cytokine Levels in Tears From Patients Diagnosed With Pterygium

Launched by CHULALONGKORN UNIVERSITY · Oct 3, 2019

Trial Information

Current as of April 24, 2025

Completed

Keywords

Hpv Infection Pterygium Cytokine Vegf Auto Inoculation

ClinConnect Summary

The main purpose of this study is to evaluate the prevalence of HPV infection in primary and recurrent pterygium and the association of HPV types collecting from conjunctiva swab and urine. The second purpose is to compare a quantity of cytokines including IL-6, IL-18 and growth factor including VEGF found in tears of patients with primary and recurrent pterygium to participants with free of ocular disease Primary hypothesis

- The prevalence of HPV infection in primary pterygium is difference with prevalence in recurrent pterygium patients.

Secondary hypothesis

* Ocular HPV infection has...

Gender

ALL

Eligibility criteria

  • Participants as primary and secondary pterygium group
  • Inclusion Criteria:
  • Age above 18 years old
  • presence of pterygium invading the cornea
  • Exclusion Criteria:
  • Other ocular inflammation that could affect the results of the study (such as conjunctivitis, keratitis, conjunctival tumor, etc) or would preclude the enrollment for safety reasons
  • Participant without ocular disease Inclusion criteria
  • Age above 18 years old Exclusion criteria
  • Presence of any ocular inflammation diseases

Trial Officials

Ngamjit Kasetsuwan

Principal Investigator

Department of Ophthalmology, Chulalongkorn University

About Chulalongkorn University

Chulalongkorn University, one of Thailand's premier academic institutions, is dedicated to advancing medical research and enhancing healthcare outcomes through innovative clinical trials. With a strong emphasis on collaboration and interdisciplinary approaches, the university leverages its extensive resources and expertise in various medical fields to conduct rigorous scientific investigations. Chulalongkorn University aims to contribute to global health advancements by fostering a culture of excellence in research, education, and community service, ultimately improving patient care and public health standards.

Locations

Bangkok, , Thailand

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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