Microbiome and Immunogenity of Saliva During Orthodontic Therapy

Launched by MEDICAL UNIVERSITY OF VIENNA · Oct 23, 2019

Keywords

ClinConnect Summary

Adult patients (18 years and older) from the Clinical Division of Orthodontics at the University Clinic of Dentistry Vienna will be invited to participate in this pilot microbiologic study according to defined inclusion/exclusion criteria after giving their consent. This study is a pilot project and therefore no sample size calculation will be made. Twenty patients will be treated with Invisalign® aligners and twenty patients will receive multibracket therapy. A previous microbiological study showed that lingual orthodontic therapy has a short-term effect on oral microflora. Another microbi...

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Eligibility criteria

• Inclusion Criteria:
• • Class I skeletal relationship
• • Normo-divergent Frankfort Mandibular-Plane Angle
• • Minimal mandibular crowding in range from 1 to 3 according to Little's Index (Little 1975)
• Exclusion Criteria:
• • Smoking habit
• • Presence of extensive dental restorations in proximity to the gingival margin
• • Presence of fixed bridges/crowns or partial dentures
• • Previous periodontal nonsurgical treatment (such as full mouth disinfection, quadrant-by-quadrant therapy, full mouth debridement) within the past year
• • Medications such as antibiotics, steroids, or nonsteroidal anti-inflammatory drugs within the past 6 months.
• • Plaque Index \> 20% before start of treatment Diabetes Pregnancy