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Search / Trial NCT04200105

EBUS-TBNA vs Acquire TBNB

Launched by ROYAL BROMPTON & HAREFIELD NHS FOUNDATION TRUST · Dec 13, 2019

Trial Information

Current as of May 08, 2025

Unknown status

Keywords

ClinConnect Summary

The causes of mediastinal lymphadenopathy include infection, reactive lymphadenopathy, granulomatous disorders, and malignancy (metastases from various primaries, lymphoma, thymoma, neurogenic tumours). Radiological appearances are usually inadequate at providing a definitive diagnosis. In granulomatous disorders such as sarcoidosis as well as certain infections including tuberculosis, there is frequently mediastinal or hilar lymph node involvement without evidence of disease activity in other organs or lymph node groups. In malignancy, the metastatic involvement of lymph nodes has importan...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Scheduled for EBUS-TBNA as part of clinical care
  • 2. Lymph node size ≥5mm on CT scan
  • 3. Age \> 18 years
  • 4. Written informed consent
  • Exclusion Criteria:
  • 1. Contraindication to needle biopsy (e.g. coagulopathy, anticoagulation, thrombocytopenia, other bleeding diathesis)
  • 2. Inability to obtain informed consent

About Royal Brompton & Harefield Nhs Foundation Trust

Royal Brompton & Harefield NHS Foundation Trust is a leading specialist healthcare provider in the United Kingdom, renowned for its expertise in cardiothoracic medicine and respiratory care. Committed to advancing clinical research and improving patient outcomes, the Trust conducts a diverse range of clinical trials aimed at exploring innovative treatments and therapies. With a multidisciplinary team of clinicians and researchers, the Foundation Trust fosters a collaborative environment that prioritizes patient safety and ethical standards, contributing significantly to the global body of medical knowledge and enhancing the quality of care for patients with complex health conditions.

Locations

London, , United Kingdom

Patients applied

0 patients applied

Trial Officials

Samuel V Kemp, MBBS

Principal Investigator

Royal Brompton and Harefield NHS FT

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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