EBUS-TBNA vs Acquire TBNB
Launched by ROYAL BROMPTON & HAREFIELD NHS FOUNDATION TRUST · Dec 13, 2019
Trial Information
Current as of May 08, 2025
Unknown status
Keywords
ClinConnect Summary
The causes of mediastinal lymphadenopathy include infection, reactive lymphadenopathy, granulomatous disorders, and malignancy (metastases from various primaries, lymphoma, thymoma, neurogenic tumours). Radiological appearances are usually inadequate at providing a definitive diagnosis. In granulomatous disorders such as sarcoidosis as well as certain infections including tuberculosis, there is frequently mediastinal or hilar lymph node involvement without evidence of disease activity in other organs or lymph node groups. In malignancy, the metastatic involvement of lymph nodes has importan...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Scheduled for EBUS-TBNA as part of clinical care
- • 2. Lymph node size ≥5mm on CT scan
- • 3. Age \> 18 years
- • 4. Written informed consent
- Exclusion Criteria:
- • 1. Contraindication to needle biopsy (e.g. coagulopathy, anticoagulation, thrombocytopenia, other bleeding diathesis)
- • 2. Inability to obtain informed consent
About Royal Brompton & Harefield Nhs Foundation Trust
Royal Brompton & Harefield NHS Foundation Trust is a leading specialist healthcare provider in the United Kingdom, renowned for its expertise in cardiothoracic medicine and respiratory care. Committed to advancing clinical research and improving patient outcomes, the Trust conducts a diverse range of clinical trials aimed at exploring innovative treatments and therapies. With a multidisciplinary team of clinicians and researchers, the Foundation Trust fosters a collaborative environment that prioritizes patient safety and ethical standards, contributing significantly to the global body of medical knowledge and enhancing the quality of care for patients with complex health conditions.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
London, , United Kingdom
Patients applied
Trial Officials
Samuel V Kemp, MBBS
Principal Investigator
Royal Brompton and Harefield NHS FT
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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