DeFect cLOsure After Colonic ESD With underwaTer Technique

Launched by CHINESE UNIVERSITY OF HONG KONG · Dec 28, 2019

Keywords

ClinConnect Summary

Endoscopic submucosal dissection (ESD) is a minimally invasive technique that has been increasingly applied to superficial colorectal tumours over the past two decades (1, 2). Although serious complications with this procedure are uncommon, both significant delayed haemorrhage (1-2%) and perforation (4-6%) are recognised complications (3). Although perforation is generally recognised and treated at time of endoscopy, delayed bleeding often requires repeat readmission and endoscopy for haemorrhage control. There is growing evidence to support prophylactic clip closure of mucosal defects to r...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients undergoing elective endoscopic resection
• • Colorectal superficial neoplasm with a resultant mucosal defect of ≥20mm
• • Age \>18 years old
• Exclusion Criteria:
• • Patients on anticoagulation (Warfarin or other direct oral anticoagulants)
• • Muscular perforation during the endoscopic resection
• • Incomplete endoscopic resection
• • Lesions arising from surgical anastomotic site
• • Marked electrolyte abnormalities
• • Other cases deemed by the examining physician as unsuitable for safe treatment
• • Patients who refused to participate