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Search / Trial NCT04226326

Investigating the Utility of Remote Index of Microvascular Resistance in Patients With Chronic Total Occlusion

Launched by UNIVERSITY OF CHICAGO · Jan 8, 2020

Trial Information

Current as of May 19, 2025

Completed

Keywords

Microvascular Resistance Percutaneous Coronary Intervention

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • age ≥ 21 years
  • seen at University of Chicago Medical center with a planned PCI of a single CTO vessel
  • must have either stable angina or angina equivalent
  • must have a CTO with a clear donor vessel supplying most of the collaterals.
  • Exclusion Criteria:
  • subjects with a pacemaker or implantable cardioverter defibrillator
  • contraindication to cardiac MRI, adenosine, heparin, or nitroglycerin
  • cardiac transplantation
  • Estimated glomerular filtration rate (eGFR) ≤ 30 mL/min/1.73m2, given the risk of contrast-induced nephropathy (CIN) and nephrogenic systemic fibrosis (NSF) associated with iodinated and gadolinium-based contrast agents, respectively, in patients with significant renal dysfunction
  • Women who may potentially be pregnant will receive a pregnancy test and be excluded if pregnant
  • Vulnerable populations such as children, college students, prisoners, non-English speakers, and those with diminished decision-making capacity
  • Inability or refusal to consent for the study.

About University Of Chicago

The University of Chicago is a prestigious research institution renowned for its commitment to advancing medical science through innovative clinical trials. With a robust infrastructure that supports multidisciplinary collaboration, the University actively engages in cutting-edge research across various therapeutic areas. Its dedicated team of experienced investigators and state-of-the-art facilities enable the University of Chicago to conduct rigorous clinical studies aimed at improving patient outcomes and translating scientific discoveries into tangible healthcare solutions. The institution prioritizes ethical standards and patient safety, ensuring that all trials adhere to the highest regulatory guidelines and best practices in clinical research.

Locations

Chicago, Illinois, United States

Patients applied

0 patients applied

Trial Officials

John Blair, MD

Principal Investigator

University of Chicago

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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