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Search / Trial NCT04242901

4-week Serial FIT Analysis in Patients With CRC

Launched by NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST · Jan 24, 2020

Trial Information

Current as of May 01, 2025

Completed

Keywords

Fit Symptomatic Fit

ClinConnect Summary

Colorectal cancer (CRC) remains a leading cause of cancer death in the UK and worldwide. Improving outcomes depends in part on achieving earlier diagnosis of the disease.

The Faecal Immunochemical Test (FIT) is replacing the less accurate Faecal Occult Blood Test (FOBT) in the UK and has the potential to help achieve earlier stage diagnosis of CRC. Whilst FIT has been validated as a screening test for the Bowel Cancer Screening Programme (BCSP), its role in diagnosing CRC in symptomatic populations is yet to be defined.

Nottingham is a pioneering centre using FIT to stratify risk and dete...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Histologically confirmed colorectal cancer
  • Exclusion Criteria:
  • Less than 18 years old
  • Not attending Nottingham University Hospitals for diagnosis/treatment (attending another trust)
  • No histological diagnosis of colorectal cancer
  • Unable to provide informed consent - for example due to language barriers or lacking capacity to join study

About Nottingham University Hospitals Nhs Trust

Nottingham University Hospitals NHS Trust is a leading healthcare provider in the UK, dedicated to delivering high-quality patient care and advancing medical research. Comprising two major hospitals, Queen's Medical Centre and Nottingham City Hospital, the Trust is at the forefront of clinical innovation and education. With a strong emphasis on translational research, Nottingham University Hospitals NHS Trust actively sponsors clinical trials aimed at improving treatment outcomes and understanding various health conditions. The Trust collaborates with academic institutions, healthcare professionals, and industry partners to foster a robust research environment that enhances clinical practice and contributes to evidence-based medicine.

Locations

Nottingham, Nottinghamshire, United Kingdom

Patients applied

0 patients applied

Trial Officials

David Humes, MBBS

Principal Investigator

Nottingham University Hospitals NHS Trust

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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