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Search / Trial NCT04271826

Grey Zone Appendicitis: Role of Blood Test Biomarkers to Detect Early Appendicitis and to Decrease the Incidence of Negative Appendectomy

Launched by ZAGAZIG UNIVERSITY · Feb 14, 2020

Trial Information

Current as of May 21, 2025

Completed

Keywords

ClinConnect Summary

INTRODUCTION Acute appendicitis is a very common surgical emergency worldwide, with a lifetime risk reported to be 7-8%..Accordingly, appendectomy is the most frequently performed operation worldwide.

Many surgical centers attempt to reduce surgical procedures performed during the night, and delaying appendectomy for 12-24 h does not seem to increase complications

Despite thorough research, the diagnosis of acute appendicitis is still difficult and remains the most common problem in clinical surgery.

In addition to clinical examination of the patients with appendicitis, ultrasonography a...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age: more than 14years of both sexes.
  • Non pregnant female.
  • Patients taking analgesics. .Patients who diagnosed to have grey zone diagnosis of acute appendicitis (Alvarado score 5-6).
  • Exclusion Criteria:
  • Alvarado score \>6 or \< 5.
  • Cases of sure acute appendicitis.
  • Documented Liver disease, biliary disease (congenital or acquired), hemolytic diseases and history of alcoholism.
  • 4) Cases revealed other pathology than appendicitis by CT and laparoscopy.

About Zagazig University

Zagazig University, a prominent educational and research institution located in Egypt, plays a pivotal role in advancing medical knowledge and promoting health innovations through its clinical trials. With a commitment to excellence in research, the university leverages its diverse expertise and state-of-the-art facilities to conduct rigorous clinical studies that aim to improve patient care and outcomes. By fostering collaboration among multidisciplinary teams, Zagazig University contributes significantly to the global medical community, ensuring that its clinical trials adhere to the highest ethical standards and regulatory requirements.

Locations

Zagazig, Sharkia, Egypt

Patients applied

0 patients applied

Trial Officials

tamer A. alnaimy, MD

Principal Investigator

Zagazig University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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