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Search / Trial NCT04341662

A Clinical Trial to Study the Effectiveness of a Care Bundle to Prevent Bleeding After a Woman Has Given Birth

Launched by UNIVERSITY OF BIRMINGHAM · Apr 8, 2020

Trial Information

Current as of June 12, 2025

Completed

Keywords

Post Partum Haemorrhage Early Detection Blood Loss Measurement Oxytocin Tranexamic Acid

ClinConnect Summary

The aim of this trial is evaluate the implementation of early detection and the use of the WHO MOTIVE 'first response' treatment bundle for PPH on clinical, implementation and resource use outcomes. The investigators will evaluate the implementation through mixed-methods and carry out a health economic evaluation from the public healthcare system perspective. The investigators will use a multi-country, parallel cluster randomised trial design with a baseline control phase, along with mixed-methods and health economic evaluations. The trial is conducted in secondary level health facilities i...

Gender

FEMALE

Eligibility criteria

  • Cluster: Health facility is the randomisation unit. Health facilities are eligible for inclusion if they have 1000 to 5000 births a year and provide comprehensive obstetric care with ability to perform surgery for PPH. Health facilities are selected based on being administratively and geographically distinct from each other. Pre-existing implementation of early detection or bundled approach are exclusion criteria
  • Research participants: All healthcare providers attending vaginal births at the study facilities.
  • Patients: All verified vaginal births in the study facilities

About University Of Birmingham

The University of Birmingham is a leading research institution in the UK, renowned for its commitment to advancing medical science and improving health outcomes through innovative clinical research. With a strong emphasis on collaboration, the university engages in multidisciplinary studies that leverage cutting-edge technology and expertise across various fields. Its dedicated clinical trial infrastructure supports rigorous investigation and the ethical conduct of research, ensuring that findings contribute meaningfully to the scientific community and public health. Through its initiatives, the University of Birmingham aims to translate research discoveries into tangible benefits for patients and healthcare systems alike.

Locations

Johannesburg, , South Africa

Karachi, , Pakistan

Nairobi, , Kenya

Cape Town, , South Africa

Dar Es Salaam, , Tanzania

Karachi, , Pakistan

Kano, , Nigeria

Colombo, , Sri Lanka

Patients applied

0 patients applied

Trial Officials

Arri Coomarasamy, MD

Principal Investigator

University of Birmingham

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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