Awake Prone Positioning to Reduce Invasive VEntilation in COVID-19 Induced Acute Respiratory failurE

Launched by UNIVERSITY COLLEGE HOSPITAL GALWAY · Apr 14, 2020

Keywords

ClinConnect Summary

Prone positioning (PP) is an adjunctive therapy used that has been proven to save lives in sedated patients with confirmed moderate-severe acute respiratory distress syndrome (ARDS) receiving invasive mechanical ventilation (MV). PP involves placing patients in the prone, i.e. face down position for time periods of up to 16 hours per day. PP promotes lung homogeneity, improves gas exchange and respiratory mechanics permitting reduction of ventilation intensity, and reducing ventilator-induced lung injury (VILI).

Maintaining self-ventilation is associated with increased aeration of dependen...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Suspected or confirmed COVID19 infection
• • Bilateral Infiltrates on CXR
• • SpO2 \<94% on FiO2 40% by either venturi facemask or high flow nasal cannula
• • RR \<40
• • Written informed consent
• Exclusion Criteria:
• • Age \<18
• • Uncooperative or likely to be unable to lie on abdomen for 16 hours
• • Receiving comfort care only
• • Multi-organ failure
• • RR\>40
• • Contraindication to PP (e.g. vomiting, abdominal wound, unstable pelvic/spinal lesions, pregnancy \>20/40 gestation, severe brain injury).