Traditional Chinese Medicine for the Treatment of Perennial Allergic Rhinitis on Gut Microbiota and Immune-modulation
Launched by CHANG GUNG MEMORIAL HOSPITAL · May 11, 2020
Trial Information
Current as of June 13, 2025
Completed
Keywords
ClinConnect Summary
Perennial allergic rhinitis is an important disease in traditional Chinese medicine (TCM) due to its high prevalence rate in Taiwan. In our previous studies, a new mixed formula of Chinese herbs was evaluated for the treatment of allergic rhinitis. In these studies, we found that immunoduoatory effects of Chinese medicine include: CD4+ T lymphocytes; Regulatory T cells; Dendritic cells, and Regulatory B cells. These results allow us to confirm the immunomodulatory effects of mixed formula of traditional Chinese medicine. In recent years, more and more attention has been paid to the effects ...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Volunteer for study enrollment and sign inform consent
- • Mite allergy confirmed by MAST test
- • Over 20 years old
- • Will have their blood collected twice and stool samples
- • Allergic rhinitis patients in the acute phase will be treated with mixed formula of Chinese medicine for one months
- Exclusion Criteria:
- • Women who are pregnant or breast-feeding
- • Under treatment of western medicine including steroid, antihistamine, leukotriene inhibitor, immunosuppressant or stop above medication less than one month
- • Under acute inflammatory disease such as pneumonia, sinusitis, bronchitis and so on vasomotor type allergic rhinitis
- • History of allergy or adverse effect to Chinese herbs, poor compliance of herbal medicine severe organ function impairment, such as heart failure, liver failure, renal failure (eGFR \<60 mL/min/1.73 m2)
About Chang Gung Memorial Hospital
Chang Gung Memorial Hospital, one of the largest healthcare organizations in Taiwan, is renowned for its commitment to advancing medical research and improving patient care. As a clinical trial sponsor, the hospital leverages its extensive clinical expertise and state-of-the-art facilities to conduct innovative research across various medical disciplines. With a focus on collaboration and ethical practices, Chang Gung Memorial Hospital aims to contribute to the global body of medical knowledge through rigorous clinical trials that enhance treatment options and improve health outcomes for patients.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Taoyuan, , Taiwan
Patients applied
Trial Officials
Sien-hung Yang, Ph.D
Study Director
Chang Gung Memorial Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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