Prehabilitation of Elderly Patients With Frailty Syndrome Before Elective Surgery (PRAEP-GO)

Launched by CHARITE UNIVERSITY, BERLIN, GERMANY · Jun 1, 2020

Keywords

ClinConnect Summary

The PRAEP-GO trial is studying how a special program can help elderly patients who are frail before they undergo elective surgery. The program includes a three-week plan to prepare patients physically and mentally, and it starts with a meeting to discuss treatment options. Researchers want to see if this approach makes it easier for patients to recover after surgery and whether it reduces their need for extra care a year later. They are looking for about 1,400 participants across different centers in the country.

To be eligible for this study, you must be at least 70 years old and scheduled for surgery that will take more than an hour under anesthesia. You also need to show signs of frailty, which means you might have some health challenges that could affect your recovery. Participants will receive personalized support during the prehabilitation program, and their progress will be closely monitored. This research is important because it aims to improve the quality of life for older patients after surgery and to see if preparing them in this way is cost-effective.

Gender

ALL

Eligibility criteria

• Study patients:
• Inclusion Criteria:
• • Age ≥ 70 years
• • Consent by Patient or Legal Representative
• • Elective surgery planned
• • Expected anesthesia duration≥ 60 min
• • Statutory health insurance
• • Frailty syndrome (≥1 positive out of 5 standardized parameters according to the Physical Frailty Phenotype according to Fried et. al.)
• Exclusion Criteria:
• • Severe cardiac or pulmonary disease (NYHA IV, Gold IV)
• • Intracranial interventions
• • Moribund patients (palliative situation)
• • Not enough language skills
• • Participation in another interventional rehabilitation study or other interventional clinical trial that has not been approved by the study management committee (Exception: Participation in adjuvant intervention study)