Letrozole Pretreatment With Misoprostol Induction of Abortion in First Trimester Missed Abortion
Launched by SHEREEN RADY ABOU EL-FETOUH · Oct 10, 2020
Trial Information
Current as of May 08, 2025
Unknown status
Keywords
ClinConnect Summary
Intervention type: drug
Intervention name: letrozole then misoprostol
Description :letrozole 2.5mg twice per day for 2days then misoprostol 800mcg for all patients to induce abortion
Arm group label:study group
Intervention type :drug
Intervention name:placebo then misoprostol
Description : placebo for 2days then 800mcg misoprostol to all patients to induce abortion
Arm group label: control group
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • 1. Maternal age more than 18 years old.
- • 2. Gestational age less than 13 weeks confirmed by ultrasound scan on day 1 of the study.
- • 3. Hemoglobin \>10 g/dl
- • 4. Missed abortion
- Exclusion Criteria:
- • 1. Mullerian Uterine anomalies as septate, bicornuate uterus.
- • 2. Fibroid uterus.
- • 3. Coagulopathy.
- • 4. Medical disorder that contraindicate induction of abortion.
- • 5. Allergy to misoprostol or letrozole.
- • -
About Shereen Rady Abou El Fetouh
Shereen Rady Abou El-Fetouh is a dedicated clinical trial sponsor with extensive experience in advancing medical research and innovation. Committed to improving patient outcomes, she focuses on a range of therapeutic areas, leveraging her expertise to design and conduct rigorous clinical studies. Her strategic approach emphasizes collaboration with healthcare professionals and regulatory bodies to ensure adherence to the highest ethical and scientific standards. With a passion for translating research findings into tangible health solutions, Shereen is dedicated to fostering advancements that benefit patients and the medical community alike.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
shereen khedr
Principal Investigator
AinShams University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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