Characterising Frailty Using Magnetic Resonance Imaging

Launched by UNIVERSITY OF NOTTINGHAM · Oct 28, 2020

Keywords

ClinConnect Summary

The study will recruit females aged over 65 years (n=51), from those attending hospital clinics for older people at both campuses of Nottingham University Hospitals National Health Service (NHS) Trust. A member of the clinical care team working within the clinic will identify potential participants who are 'frail', 'mildly frail/vulnerable' and 'non-frail' using the Clinical Frailty Scale (measured as part of routine care), and the electronic Frailty Index. Clinic staff will make the initial approach to patients about the study and if the individual is interested in taking part, clinic staf...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Females aged over 65 years of age attending Nottingham University Hospitals NHS Trust 'falls and bone health' and general geriatric clinics;
• • Able to provide informed consent;
• • Once 17 participants have been recruited to any of the three study groups (non-frail, pre-frail, frail) the study will be restricted to people in the remaining groups only;
• • Good understanding of written and spoken English.
• Exclusion Criteria:
• • Metal within the body which could be affected by MRI;
• • Any other contraindications for MRI scan (e.g. brain aneurysm clips, permanent pacemaker);
• • Over 190.5 cm in height
• • Inability to lie on back within the MRI scanner
• • Mobility limitations which would prevent the individual transferring onto equipment
• • Unable to speak or understand English;
• • In receipt of end of life care;
• • Lacking the mental capacity to understand the requirements of study participation and provide consent.