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Search / Trial NCT04614129

Lung Cancer Risk and Early Detection in Firefighters

Launched by MASSACHUSETTS GENERAL HOSPITAL · Oct 28, 2020

Trial Information

Current as of May 07, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is looking at lung cancer risk and early detection specifically in firefighters. Researchers want to understand how the findings from a special type of lung scan (called LDCT) may differ between current and retired firefighters compared to non-firefighters. The study will also explore how different work exposures might affect these findings and if a new test can help better assess the risk of lung nodules found during screening.

To participate, you must be between 40 and 80 years old, have at least 10 years of firefighting experience, and either be a current or retired firefighter. You should not have a personal history of lung cancer and must be willing to undergo LDCT screening or have recently done so. Unfortunately, if you have any active cancer, you won't be eligible for this study. If you join, you can expect to have your lung scans reviewed and possibly take part in additional assessments to help researchers learn more about lung health in firefighters.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 40-80 years of age or with 10 years of firefighting experience
  • Current or retired firefighters
  • No personal history of lung cancer
  • Willing and able to receive LDCT screening at MGH or who have been screened via LDCT within the past year at MGH or another institution, and are willing to release their images to the study
  • Exclusion Criteria:
  • Any active cancer (undergoing treatment or diagnosed within the past 5 years)

About Massachusetts General Hospital

Massachusetts General Hospital (MGH) is a leading academic medical center located in Boston, Massachusetts, renowned for its commitment to advancing medical research and patient care. As a prominent teaching hospital affiliated with Harvard Medical School, MGH plays a pivotal role in clinical trials across a wide range of disciplines, including cardiology, oncology, neurology, and more. The institution is dedicated to fostering innovative research that translates into effective therapies and improved health outcomes. MGH's Clinical Trials Office provides comprehensive support to facilitate the design, implementation, and management of clinical studies, ensuring adherence to the highest ethical standards and regulatory compliance. With a focus on collaboration and patient-centered care, MGH strives to enhance medical knowledge and contribute to the future of healthcare.

Locations

Boston, Massachusetts, United States

Patients applied

0 patients applied

Trial Officials

Erica T Warner, ScD

Principal Investigator

Massachusetts General Hospital

Lecia V Sequist, MD

Principal Investigator

Massachusetts General Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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