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Search / Trial NCT04632394

Multimodality Assessment of Ventricular Scar Arrhythmogenicity.

Launched by ST GEORGE'S, UNIVERSITY OF LONDON · Nov 11, 2020

Trial Information

Current as of June 12, 2025

Completed

Keywords

Ventricular Tachycardia Ablation Cardiac Mri Computational Modelling

ClinConnect Summary

Patients will be eligible for this trial both from referrals as an outpatient, where VT has been detected on a heart rhythm monitor or ECG (electrical heart tracing), or as an inpatient where they have been admitted to hospital with symptoms of VT. Our study investigators will discuss the research with the patient and give them the relevant information in an understandable format as part of a Patient Information Sheet so that they can make an informed decision about whether or not to participate in the research.

An MRI scan of the heart is a standard investigation for patients presenting w...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adult inpatients admitted to St George's Hospital London with sustained ventricular tachycardia or outpatients identified from the arrhythmia clinic with significant monomorphic ventricular tachycardia noted on cardiac monitoring who:
  • Have sustained, monomorphic scar-dependent ventricular tachycardia
  • Are symptomatic
  • Failed, unable or unwilling to tolerate anti-arrhythmic medications
  • Able to have a cardiac MRI
  • Have a life expectancy \> 1 year
  • At least 40 days following a myocardial infarction
  • Exclusion Criteria:
  • Patients under the age of 18
  • Patients who are unable to give informed consent
  • Pregnant patients
  • Unable to have cardiac MRI
  • Prohibitive procedural risk
  • Unable to tolerate the ablation procedure due to haemodynamic instability

About St George's, University Of London

St George's, University of London is a leading academic institution dedicated to advancing healthcare through innovative research and education. As a prominent clinical trial sponsor, the university leverages its expertise in biomedical sciences, medicine, and health professions to conduct rigorous clinical studies aimed at improving patient outcomes. With a commitment to ethical practices and collaboration across disciplines, St George's fosters an environment that encourages groundbreaking discoveries and the translation of research findings into clinical applications, ultimately enhancing the quality of care in diverse medical fields.

Locations

London, , United Kingdom

Patients applied

0 patients applied

Trial Officials

Magdi Saba, MD

Study Director

St George's Hospital / SGUL

Anthony Li, MD

Study Director

St George's Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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