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Search / Trial NCT04640649

Prediction of Progression of Age-Related Macular Degeneration

Launched by UNIVERSITY OF ILLINOIS AT CHICAGO · Nov 17, 2020

Trial Information

Current as of May 12, 2025

Unknown status

Keywords

ClinConnect Summary

More than 90% of patients with advanced AMD have severe vision loss. Predicting AMD progression from an early or intermediate stage is crucial, since prompt intervention after a choroidal neovascularization (CNV) event and geographic atrophy (GA) monitoring can greatly improve visual outcomes. Patients at higher risk of progression should have more frequent follow-up visits, since progression often occurs before any visual changes are noticed by the patient. Previous work has determined the risk factors for AMD progression based on drusen features in fundus photos, Optical Coherence Tomogra...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Non-neovascular AMD at baseline in at least one eye with no signs of GA,
  • \> 45 years of age,
  • willingness to participate through a signed consent form.
  • Exclusion Criteria:
  • Pregnant women and vulnerable populations
  • Participation in an investigational trial that involves treatment with any drug (with the exception of vitamins or minerals) within 3 months prior to Day 1.
  • Any history of macular pathology unrelated to AMD affecting vision or contributing to the presence of intraretinal or subretinal fluid

About University Of Illinois At Chicago

The University of Illinois at Chicago (UIC) is a leading academic institution renowned for its commitment to advancing health sciences through innovative research and clinical trials. With a strong emphasis on interdisciplinary collaboration, UIC harnesses the expertise of its diverse faculty and state-of-the-art facilities to conduct cutting-edge clinical studies aimed at improving patient outcomes. The university's robust infrastructure for clinical research, combined with its dedication to ethical standards and regulatory compliance, positions UIC as a pivotal contributor to the development of new treatments and therapies in various medical fields. Through strategic partnerships and community engagement, UIC strives to translate research findings into real-world applications, enhancing the health and well-being of populations locally and globally.

Locations

Patients applied

0 patients applied

Trial Officials

Joelle A Hallak, PhD

Principal Investigator

University of Illinois at Chicago

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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