Fresh Corneal Lenticule Implantation in Macular Corneal Distrophy With Relex Smile Surgery
Launched by EYE HOSPITAL PRISTINA KOSOVO · Nov 21, 2020
Trial Information
Current as of May 22, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Macular Corneal Dystrophy is a severe form of stromal corneal dystrophy characterized by bilateral cloudy regions within hazy stroma and eventually severe visual impairment.
Most cases of MCD are caused by mutations in the CHST6 gene encoding a protein involved in the production of keratan sulfate, which plays a role in the maintenance of corneal transparency.
According to biomechanical instability of corneal metabolism (abnormal increase collagenase activity, decrease proteinase inhibitors, excessive premature keratocyte apoptosis, increase cytokine binding) at corneal dystrophies. Fresh...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • indications for penetrating keratoplasty
- • low transparec of corneae
- • low visual acuity
- Exclusion Criteria:
- • active anterior segment pathology
- • previous corneal or anterior segment surgery
- • any infection
About Eye Hospital Pristina Kosovo
Eye Hospital Pristina, located in Kosovo, is a leading clinical research institution dedicated to advancing ophthalmic care through rigorous clinical trials. Committed to improving patient outcomes, the hospital specializes in innovative treatments and technologies in eye health. With a multidisciplinary team of experienced ophthalmologists and researchers, Eye Hospital Pristina actively participates in collaborative studies aimed at enhancing the understanding and management of various eye conditions. The institution prioritizes patient safety and ethical standards, ensuring the highest quality of care and adherence to international research protocols.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Pristina, , Kosovo
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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