Nomogram to Predict Breast Cancer Related Lymphedema

Launched by WUHAN UNIVERSITY · Dec 7, 2020

Keywords

ClinConnect Summary

This clinical trial is studying a new way to predict and prevent arm swelling, known as lymphedema, in women who have undergone surgery for breast cancer. Researchers believe that keeping certain lymphatic pathways intact during surgery may help prevent this condition, which can occur after the removal of lymph nodes in the armpit area. The trial aims to identify women at higher risk for lymphedema and provide special surgical techniques to protect their arm lymphatics, potentially reducing the chance of swelling after surgery.

To participate in this trial, women aged 18 and older with invasive breast cancer may be eligible if they have certain characteristics, such as positive lymph nodes found before surgery. However, women who have received chemotherapy before surgery or have a history of breast cancer are not eligible. Participants can expect to receive specialized care and may have a chance to help improve future treatments for others facing similar challenges. This trial is currently recruiting, and your involvement could make a difference in understanding and preventing lymphedema.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Patients aged 18 years or older with T1-3 invasive breast cancer;
• • Clinically node-positive breast cancer, defined as positive on preoperative axillary palpation, ultrasound examination, and computed tomography scan with contrast;
• • Patients who underwent mastectomy with a positive sentinel lymph node (SLN);
• • Patients who underwent breast-conserving surgery containing more than two positive SLNs.
• Exclusion Criteria:
• • Neoadjuvant chemotherapy;
• • Previous history of breast cancer.