Study of Lactobacillus in Adjuvant Treatment of RVVC

Launched by PEKING UNIVERSITY SHENZHEN HOSPITAL · Jan 6, 2021

Keywords

ClinConnect Summary

This clinical trial is looking at whether adding a specific type of bacteria called Lactobacillus to the usual treatment for recurrent vulvovaginal candidiasis (RVVC) helps prevent future infections. RVVC is a condition where women frequently experience yeast infections, which can cause symptoms like irritation and unusual discharge. The researchers want to find out if taking Clotrimazole vaginal tablets along with oral Lactobacillus is more effective than using Clotrimazole alone.

To participate in this study, women must be at least 18 years old and experiencing symptoms of RVVC. However, certain individuals are not eligible, such as those who have recently taken antibiotics, are pregnant or breastfeeding, or have specific health issues like severe gastrointestinal or heart problems. If you join the trial, you will receive the treatment being studied, and your progress will be monitored by healthcare professionals. This trial is currently recruiting participants, so it’s a good opportunity for those looking for new ways to manage their condition.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Women be at least 18 years of age
• • Have symptoms of vulva irritation and or abnormal discharge
• • Meet the clinical criteria for RVVC
• • Willing to participate in research
• Exclusion Criteria:
• • 1. Taking / injecting antibiotics in the past two weeks;
• • 2. A woman who intends to be pregnant, pregnant or lactating;
• • 3. Long term use of contraceptives and immunosuppressants;
• • 4. Postmenopausal;
• • 5. There was no same fixed sexual partner (RSP) before and after treatment
• • 6. Patients with severe gastrointestinal diseases, including colorectal cancer, IBS, IBD, chronic or acute diarrhea, long-term constipation, etc., or receiving gastrointestinal surgery and abdominal surgery within one year, such as cholecystectomy;
• • 7. Patients with severe heart, liver and kidney dysfunction, mental diseases, infectious diseases, tumors, severe anemia, and severe autoimmune diseases (such as rheumatoid arthritis, lupus erythematosus, etc.)