Effect of Different Probiotic Strains in Hypercholesterolemic Patients
Launched by EASTERN MEDITERRANEAN UNIVERSITY · Jan 5, 2021
Trial Information
Current as of May 29, 2025
Completed
Keywords
ClinConnect Summary
In the light of recent studies, it has been shown that probiotics may have positive effects on hyperlipidemia. The aim of this study was to investigate the effect of probiotics mainly on blood lipids as well as homocysteine levels, glycemic control parameters and hs-CRP levels A randomized, double-blind placebo-controlled study was completed with a total of 51 individuals who have diagnosed with hyperlipidemia. Participants were randomly assigned into 3 groups according to the probiotic type they would consume, groups were as follows; Lactobacillus (probiotic group I) (n=18), Lactobacillus ...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • • Had a repeated total cholesterol level ≥200 mg/dL prior to allocate to the study group and to declined conventional lipid lowering medical treatment
- Exclusion Criteria:
- • Those with any chronic conditions other than hypercholesterolemia,
- • Individuals with inherited lipid metabolic disorders,
- • Individuals with chronic gastrointestinal disease,
- • Individuals with immunodeficiency,
- • Individuals with malignancy,
- • Individuals with mental disabilities,
- • Patients currently using any lipid lowering drugs, or an alternative treatment to lower blood cholesterol (such as probiotics) and individuals who have used antibiotics in the previous three months prior to study and
- • Pregnant or lactating women were excluded from the study.
About Eastern Mediterranean University
Eastern Mediterranean University (EMU) is a leading institution dedicated to advancing research and education in the fields of health sciences and medicine. Renowned for its commitment to innovation and academic excellence, EMU engages in clinical trials that aim to enhance healthcare outcomes and contribute to the understanding of various medical conditions. With a collaborative approach, the university works alongside local and international partners to facilitate groundbreaking research initiatives, ensuring adherence to high ethical standards and regulatory compliance. EMU's focus on multidisciplinary research fosters an environment that encourages the translation of scientific discoveries into practical applications, ultimately benefiting patients and communities in the Eastern Mediterranean region and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Famagusta, , Cyprus
Patients applied
Trial Officials
Gözde Okburan
Principal Investigator
Eastern Medittanean University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials