CT Perfusion Parameters Predict Vascular Pattern in Hepatocellular Carcinoma

Launched by SUN YAT-SEN UNIVERSITY · Jan 14, 2021

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Eligibility criteria

• Inclusion Criteria:
• • 1. age over than 18 years old
• • 2. tumor size of less than 5 cm
• • 3. Child-Pugh A class liver function
• • 4. an Eastern Cooperative Oncology Group performance status of 0
• • 5. no previous treatment for HCC
• • 6. pathological diagnosis of hepatocellular carcinoma
• • 7. adequate organ function (white blood cell count ≥3.0 × 109/L, absolute neutrophil count ≥1.5 × 109/L, platelet count ≥75 × 109/L, aspartate transaminase and alanine transaminase≤5 × upper limit of the normal, creatinine clearance rate of ≤1.5 × upper limit of the normal, and left ventricular ejection ≥45%)
• Exclusion Criteria:
• • 1. Patients who received antitumor therapy before recurrence, including radiotherapy, transarterial chemoembolization, tyrosine kinase inhibitor, and immune checkpoint inhibitor
• • 2. a known medical history of HIV infection
• • 3. pregnancy or breastfeeding
• • 4. portal vein tumor thrombosis or hepatic vein thrombosis detected by any routine imaging modality, including ultrasonography, dynamic contrast CT and MRI
• • 5. any evidence of tumor metastasis or prior recurrence
• • 6. hepatic decompensation