Evaluating the Use of 0.5 and 0.75 MAC Desflurane in Patients Undergoing Spinal Surgery
Launched by CHANGI GENERAL HOSPITAL · Jan 19, 2021
Trial Information
Current as of June 08, 2025
Completed
Keywords
ClinConnect Summary
Recording of Evoked Potentials characteristics:
The following characteristics of the evoked potential signals will be recorded:
* Amplitude: Size of the response, measured in microvolts (μV)
* Latency: Speed of the response, measured in milliseconds (ms)
* Morphology: Appearance of the response - Simple/Complex wave shape Baseline evoked potentials will be recorded at various points of surgery.
Anaesthesia variables:
At the time of recording of evoked potentials:
- Intraoperative temperature, blood pressure, ETCO2, anaesthesia depth - bispectral index monitoring (BIS), remifentanil TCI...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients aged ≥ 21 years old, scheduled for spinal surgery.
- • Patients who require SSEP/MEP and with no neurological deficits.
- • Patients of American Society of Anesthesiologist I-III physical status.
- • Consenting patients.
- • Elective procedures.
- Exclusion Criteria:
- • Patients with sensory or motor deficits preoperatively.
- • Patients with significant cardiovascular and/or respiratory disease.
- • Emergency procedures.
- • Cord injury secondary to trauma.
- • Non-consenting patients.
- • Category A patients (Prisoners).
- • Patients with previous stroke.
- • Patients with Hep C, HIV.
About Changi General Hospital
Changi General Hospital (CGH) is a leading tertiary healthcare institution in Singapore, renowned for its commitment to providing high-quality patient care and advancing medical research. As a sponsor of clinical trials, CGH leverages its state-of-the-art facilities and multidisciplinary expertise to facilitate innovative research that aims to enhance treatment options and improve patient outcomes. The hospital is dedicated to upholding rigorous ethical standards and regulatory compliance while fostering collaboration with healthcare professionals and researchers to drive advancements in medical science. Through its clinical trials, CGH seeks to contribute to the global body of knowledge and translate research findings into practical applications for better healthcare delivery.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Singapore, , Singapore
Patients applied
Trial Officials
Wai May Leong, MMed
Principal Investigator
Changi General Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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