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Search / Trial NCT04728659

Desogestrel Versus GnRH Antagonist in IVF/ICSI

Launched by CASA DI CURA PRIVATA VILLA MAFALDA · Jan 27, 2021

Trial Information

Current as of May 21, 2025

Unknown status

Keywords

Ovulation Progestin Ppos Gn Rh Antagonist

ClinConnect Summary

Study design A prospective controlled randomized clinical trial (RCT) will be conducted to assess the non inferiority of Desogestrel (75 mcg) versus a flexible GnRH antagonist protocol with ganirelix (0.25 mg/day) in ovarian stimulation cycles.All partecipants will provide informed consent after counselling for infertility treatments and routine IVF procedures.

This will be a prospective non-inferiority trial. Given the possibility of dropouts, the study will be designed to include a total of 165 patients Patients will be recruited consecutively and allocated to one of the two groups in al...

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • regular menstrual cycles over the previous 3-month period (25 - 35 days in duration)
  • basal serum FSH concentration of no more than 10 IU/L
  • Exclusion Criteria:
  • documented ovarian failure, including basal FSH above 10 IU/L or no antral follicles by ultrasound examination
  • diagnosis of polycystic ovarian syndrome
  • any controindication to ovarian stimulation treatment.

About Casa Di Cura Privata Villa Mafalda

Casa di Cura Privata Villa Mafalda is a renowned private healthcare facility committed to delivering high-quality medical services and innovative treatments. With a focus on patient-centered care, the institution combines advanced medical technology with a dedicated team of experienced professionals. Villa Mafalda is actively involved in clinical research, aiming to enhance therapeutic options and improve patient outcomes. The facility prioritizes safety and ethical standards in all its trials, fostering collaborations with leading healthcare organizations to contribute to medical advancements.

Locations

Roma, , Italy

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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