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Search / Trial NCT04749810

Observational Study of Elizaria® in aHUS Patients

Launched by AO GENERIUM · Feb 8, 2021

Trial Information

Current as of May 27, 2025

Completed

Keywords

Atypical Hemolytic Uremic Syndrome Azotemia Hemolytic Uremic Syndrome Hemolysis Syndrome Disease Pathologic Processes Uremia Kidney Diseases Urologic Diseases Anemia, Hemolytic Anemia Hematologic Diseases Thrombotic Microangiopathies Thrombocytopenia Blood Platelet Disorders

ClinConnect Summary

After screening, patients meeting all of the inclusion / non-inclusion criteria and vaccinated against meningococcal infections were treated by Elizaria®.

The study is planned to include at least 50 patients receiving Elizaria® for the aHUS treatment.

The study will consist of a screening period of up to 4 weeks, including, if necessary, immunization with meningococcal vaccine, a treatment period of 52 weeks.

Medication will be prescribed in accordance with routine medical practice. Accordingly to minimize the risks and subjectivity of assessments the methods adopted in the routine pract...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria
  • 1. Written informed consent to study participation.
  • 2. Male and female patients aged 2 months and older with documented atypical hemolytic uremic syndrome (aHUS)diagnosis.
  • 3. By the time of inclusion in the study, Elizaria® should be prescribed as a pathogenetic therapy for aHUS; Exclusion Criteria
  • 1. Intolerance to eculizumab, or other components of the drug.

About Ao Generium

Ao Generium is a pioneering biopharmaceutical company dedicated to advancing innovative therapies for the treatment of rare and complex diseases. With a strong emphasis on cutting-edge research and development, Ao Generium leverages state-of-the-art technologies and a collaborative approach to accelerate the discovery and delivery of effective medical solutions. Committed to improving patient outcomes, the company actively engages in clinical trials that push the boundaries of current treatments and aim to address unmet medical needs. Through its dedication to scientific excellence and patient-centric initiatives, Ao Generium is poised to make a significant impact in the healthcare landscape.

Locations

Kazan, , Russian Federation

Krasnoyarsk, , Russian Federation

Moscow, , Russian Federation

Moscow, , Russian Federation

Moscow, , Russian Federation

Moscow, , Russian Federation

Saint Petersburg, , Russian Federation

Saint Petersburg, , Russian Federation

Patients applied

0 patients applied

Trial Officials

Oksana A. Markova, MD

Study Chair

AO GENERIUM

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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