Antiseptic Irrigation for Pleural Infection

Launched by ALEXANDRIA UNIVERSITY · Feb 17, 2021

Keywords

ClinConnect Summary

Pleural infection is a condition that requires hospitalization for management and is associated with significant in-hospital morbidity and mortality. Predictors of poor outcome include advancing age, poor nutrition, hospital-acquired infection and impaired renal function. Medical management is centred on appropriate antibiotic treatment and fluid drainage usually by the means of an intercostal tube. Up to 30% of patients fail medical treatment and referred for surgery. A recent systematic review of adults patient with pleural infection has shown that the demographics of patients with pleura...

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Eligibility criteria

• Inclusion Criteria:
• • All adult patients admitted to hospital with pleural infection and had a chest tube inserted for treatment of the infection. Pleural infection will be defined by the presence of one of the following: a) the presence of pus in the pleural space; b) positive pleural fluid gram stain or culture; or c) pleural fluid pH \< 7.2 or pleural fluid glucose \< 40 mg/dL in the setting of acute respiratory infection.
• • Pleural collection is unilocular on pre-drainage imaging. Presence of septations on ultrasound examination is allowed.
• Exclusion Criteria:
• • Known or suspected thyroid disease
• • Allergy to iodine
• • Persistent large collection on follow up imaging 24-48 of post tube insertion that requires another drainage procedure